[HTML][HTML] Bone fracture healing in mechanobiological modeling: A review of principles and methods

MS Ghiasi, J Chen, A Vaziri, EK Rodriguez, A Nazarian - Bone reports, 2017 - Elsevier
Bone fracture is a very common body injury. The healing process is physiologically complex,
involving both biological and mechanical aspects. Following a fracture, cell migration …

Evaluating the evidentiary value of the analysis of skeletal trauma in forensic research: A review of research and practice

N Dempsey, S Blau - Forensic science international, 2020 - Elsevier
Understanding bone trauma characteristics is a fundamental component of forensic
investigations that can assist in understanding the nature of blunt trauma related deaths. The …

Computational modeling of human bone fracture healing affected by different conditions of initial healing stage

MS Ghiasi, JE Chen, EK Rodriguez, A Vaziri… - BMC musculoskeletal …, 2019 - Springer
Background Bone healing process includes four phases: inflammatory response, soft callus
formation, hard callus development, and remodeling. Mechanobiological models have been …

Motion predicts clinical callus formation: construct-specific finite element analysis of supracondylar femoral fractures

J Elkins, JL Marsh, T Lujan, R Peindl, J Kellam… - JBJS, 2016 - journals.lww.com
Background: Mechanotransduction is theorized to influence fracture-healing, but optimal
fracture-site motion is poorly defined. We hypothesized that three-dimensional (3-D) fracture …

Fixation of a split fracture of the lateral tibial plateau with a locking screw plate instead of cannulated screws would allow early weight bearing: a computational …

I Carrera, PE Gelber, G Chary… - International …, 2016 - Springer
Purpose To assess, with finite element (FE) calculations, whether immediate weight bearing
would be possible after surgical stabilization either with cannulated screws or with a locking …

A finite element analysis of relationship between fracture, implant and tibial tunnel

Y Wang, E Qi, X Zhang, L Xue, L Wang, J Tian - Scientific reports, 2021 - nature.com
The purpose of this article was to use finite element analysis (FEA) to study the relationship
of tibial tunnel (TT) with fracture pattern and implants. A computed tomography scan of full …

Individualized determination of the mechanical fracture environment after tibial exchange nailing—A simulation-based feasibility study

BJ Braun, M Orth, S Diebels, K Wickert, A Andres… - Frontiers in …, 2021 - frontiersin.org
Non-union rate after tibial fractures remains high. Apart from largely uncontrollable biologic,
injury, and patient-specific factors, the mechanical fracture environment is a key determinant …

A homeostatic-driven turnover remodelling constitutive model for healing in soft tissues

E Comellas, TC Gasser… - Journal of the Royal …, 2016 - royalsocietypublishing.org
Remodelling of soft biological tissue is characterized by interacting biochemical and
biomechanical events, which change the tissue's microstructure, and, consequently, its …

Precision medicine applications to manage multiply injured patients with orthopaedic trauma

TO McKinley, FA Lisboa, AD Horan… - … of orthopaedic trauma, 2019 - journals.lww.com
Precision medicine offers potential for improved outcomes by tailoring interventions based
on patient-specific demographics and disease-specific data. Precision methods are …

What is the stable internal fixation for the unstable and osteoporotic supracondylar femoral fractures: a finite element analysis

J Rao, J Zhang, Z Ye, L Zhang, J Xu - Journal of Orthopaedic Surgery and …, 2023 - Springer
Background Osteoporotic supracondylar femoral fractures (OSFF) have historically been
managed by the lateral anatomical locking plate with reasonable success. However, for …