Epileptogenesis is a chronic process that can be triggered by genetic or acquired factors,
and that can continue long after epilepsy diagnosis. In 2015, epileptogenesis is not a …

Prevention of epileptogenesis after brain trauma is an unmet medical challenge. Recent
molecular profiling studies have provided an insight into molecular changes that contribute …

Activity-driven transcription is a key event associated with long-lasting forms of neuronal
plasticity. Despite the efforts to investigate the regulatory mechanisms that control this …

Status epilepticus (SE) is a life-threatening condition that can give rise to a number of
neurological disorders, including learning deficits, depression and epilepsy. Many of the …

Prolonged seizures (status epilepticus) produce pathophysiological changes in the
hippocampus that are associated with large-scale, wide-ranging changes in gene …

MicroRNA (miRNA) are an important class of non-coding RNA which function as post-
transcriptional regulators of gene expression in cells, repressing and fine-tuning protein …

In this exciting era, we are coming closer and closer to bringing an anti‐inflammatory
therapy to the clinic for the purpose of seizure prevention, modification, and/or suppression …

Abstract Glial Fibrillary Acidic Protein (GFAP) is regarded as a marker of reactive
astrogliosis. Recent studies have demonstrated that signal transducer and activator of …

Uncovering the molecular mechanisms of mesiotemporal lobe epilepsy (MTLE) is critical to
identify therapeutic targets. In this study, we performed global protein expression analysis of …

Background Accumulating evidence demonstrates that certain microRNAs play critical roles
in epileptogenesis. Our previous studies found microRNA (miR)‐129–2‐3p was induced in …