Platelet δ-storage pool disease: an update

A Dupuis, JC Bordet, A Eckly, C Gachet - Journal of clinical medicine, 2020 - mdpi.com
Platelet dense-granules are small organelles specific to the platelet lineage that contain
small molecules (calcium, adenyl nucleotides, serotonin) and are essential for the activation …

[HTML][HTML] Platelet aggregation assays do not reliably diagnose platelet delta granule storage pool deficiency

WT Gunning III, L Yoxtheimer, MR Smith - Journal of Hematology, 2021 - ncbi.nlm.nih.gov
Background Patients with platelet dysfunction disorders present with a variety of
mucocutaneous bleeding symptoms including easy bruising, frequent epistaxis, bleeding …

Outpatient management of heavy menstrual bleeding in adolescent and young women with inherited platelet function disorders

CM Pennesi, EH Quint, MW Rosen, SD Compton… - Journal of Pediatric and …, 2020 - Elsevier
Abstract Study Objective To assess the treatment patterns and efficacy of hormonal (HM)
and non-HM (NHM) management of heavy menstrual bleeding (HMB) in young women with …

Platelet electron microscopy: utilizing LEAN methodology to optimize laboratory workflow

L Asher, J Hata - Pediatric and Developmental Pathology, 2020 - journals.sagepub.com
Background Platelet electron microscopy (PEM) is the gold standard methodology for
diagnosing storage pool disorder, defined as a paucity of delta granules, alpha granules, or …

Circumcision bleeding rates in patients diagnosed with delta‐storage pool deficiency later in life

HA Absi, D Stein - Pediatric Blood & Cancer, 2022 - Wiley Online Library
Background Male circumcision is a common procedure, generally performed during the
newborn period. Bleeding is an uncommon but feared complication of circumcision. Few …