Serum levels of liver enzymes, such as alanine transaminase, aspartate transaminase, and
α-fetoprotein, provide insight into liver function and are used during treatment of liver …

Hepatocellular carcinoma (HCC) is among the deadliest cancer in human malignancies. It is
the most common and severe type of primary liver cancer. However, the molecular …

Ubiquitin-like with PHD and RING finger domains 1 (UHRF1) is an essential regulator of
DNA methylation that is highly expressed in many cancers. Here, we use transgenic …

Hepatocellular carcinoma (HCC) is one of the most frequently occurring cancers with poor
prognosis, and novel diagnostic or prognostic biomarkers and therapeutic targets for HCC …

Despite advances in DNA methylome analyses of cells and tissues, current techniques for
genome-scale profiling of DNA methylation in circulating cell-free DNA (ccfDNA) remain …

Hepatocellular carcinoma (HCC) is one of the leading causes of death induced by cancer in
the modern world and majority of the cases are related to chronic hepatitis B virus (HBV) …

Epigenetic modifications such as DNA and histone methylation functionally cooperate in
fostering tumor growth, including that of hepatocellular carcinoma (HCC). Pharmacological …

Long non-coding RNA HOTAIR exerts regulatory functions in various biological processes in
cancer cells, such as proliferation, apoptosis, mobility, and invasion. We previously found …

Hepatocellular carcinoma (HCC) remains one of the most prevalent malignant diseases
worldwide, and the majority of cases are related to hepatitis B virus (HBV) infection …

PCBP1 is a multifunctional RNA-binding protein (RBP) expressed in most human cells and
is involved in posttranscriptional gene regulation. PCBP1 regulates the alternative splicing …