Introduction• Bone fracture healing and healing problems• Biomaterial scaffolds and tissue
engineering in bone formation‐Bone tissue engineering‐Biomaterial scaffolds‐Synthetic …

Clinical translation of scaffold-based bone tissue engineering (BTE) therapy still faces many
challenges despite intense investigations and advancement over the years. To address …

Bone has a capability to repair itself when it is fractured. Repair involves the generation of
intermediate tissues, such as fibrous connective tissue, cartilage and woven bone, before …

This article presents a unified clinical theory that links established facts about the physiology
of bone and homeostasis, with those involved in the healing of fractures and the …

Translation of scaffold-based bone tissue engineering (BTE) therapies to clinical use
remains, bluntly, a failure. This dearth of translated tissue engineering therapies (including …

It is becoming increasingly clear that mesenchymal stem cell (MSC) differentiation is
regulated by mechanical signals. Mechanical forces generated intrinsically within the cell in …

Fibrocartilage is an avascular tissue that is best documented in menisci, intervertebral discs,
tendons, ligaments, and the temporomandibular joint. Several of these sites are of particular …

This book covers the latest research and advancements related to articular cartilage in
biology, development, pathology, clinical applications and tissue engineering. The authors …

Mechanical environment has a crucial role in our organism at the different levels, ranging
from cells to tissues and our own organs. This regulatory role is especially relevant for …

Phenomenological computational models of tissue regeneration and bone healing have
been only partially successful in predicting experimental observations. This may be a result …