The Flavivirus genus of the Flaviviridae family of enveloped single-stranded RNA viruses
encompasses more than 70 members, many of which cause significant disease in humans …

Flaviviruses, including dengue (DENV), Zika (ZIKV), West Nile (WNV), Japanese
encephalitis (JEV), yellow fever (YFV), and tick-borne encephalitis (TBEV) viruses, pose a …

Ilhéus virus (ILHV) is a neglected mosquito-borne flavivirus. ILHV infection may lead to
Ilhéus fever, an emerging febrile disease like dengue fever with the potential to evolve into a …

Macroautophagy/autophagy is increasingly implicated in a variety of diseases, making it an
attractive therapeutic target. However, many aspects of autophagy are not fully understood …

Tembusu virus (TMUV) is an emerging flavivirus that has broken out in different regions of
China. TMUV infection has been reported to induce autophagy in duck embryo fibroblast …

In the past decade, Zika virus (ZIKV) emerged as a global public health concern. Although
adult infections are typically mild, maternal infection can lead to adverse fetal outcomes …

West Nile virus (WNV) requires programmed− 1 ribosomal frameshifting for translation of the
viral genome. The efficiency of WNV frameshifting is among the highest known. However, it …

Ankyrin repeat and LEM domain-containing 2 (ANKLE2) is a scaffolding protein with
established roles in cell division and development, the dysfunction of which is increasingly …

Duck Tembusu virus (DTMUV) is a neurotropic virus in the genus Flavivirus that causes
massive economic losses to the poultry industry in China and neighbouring countries …

Powassan virus (POWV) is an emerging tick-borne Flavivirus that causes lethal encephalitis
and long-term neurologic damage. Currently, there are no POWV therapeutics, licensed …