Interactions between NO and reactive oxygen species: pathophysiological importance in atherosclerosis, hypertension, diabetes and heart failure
G Kojda, D Harrison - Cardiovascular research, 1999 - academic.oup.com
1. Background: the concept of 'endothelial dysfunc- deficiency of either the substrate for the
enzyme NO tion' synthase or one of its critical co-factors. Alterations of endothelial cell …
enzyme NO tion' synthase or one of its critical co-factors. Alterations of endothelial cell …
Redox theory of aging: implications for health and disease
Genetics ultimately defines an individual, yet the phenotype of an adult is extensively
determined by the sequence of lifelong exposures, termed the exposome. The redox theory …
determined by the sequence of lifelong exposures, termed the exposome. The redox theory …
PTEN-inducible kinase 1 (PINK1)/Park6 is indispensable for normal heart function
Oxidative stress is caused by an imbalance between reactive oxygen species (ROS)
production and the ability of an organism to eliminate these toxic intermediates. Mutations in …
production and the ability of an organism to eliminate these toxic intermediates. Mutations in …
N‐acetylcysteine replenishes glutathione in HIV infection
SC De Rosa, MD Zaretsky, JG Dubs… - European journal of …, 2000 - Wiley Online Library
Background Glutathione (GSH) deficiency is common in HIV‐infected individuals and is
associated with impaired T cell function and impaired survival. N‐acetylcysteine (NAC) is …
associated with impaired T cell function and impaired survival. N‐acetylcysteine (NAC) is …
Regulation of hypertrophic and apoptotic signaling pathways by reactive oxygen species in cardiac myocytes
A Sabri, HH Hughie, PA Lucchesi - Antioxidants and Redox …, 2003 - liebertpub.com
Increasing evidence suggests that oxidative and nitrosative stress play an important role in
regulation of cardiac myocyte growth and survival. The cardiovascular system is …
regulation of cardiac myocyte growth and survival. The cardiovascular system is …
[HTML][HTML] Cardiac remodeling and physical training post myocardial infarction
MA Garza, EA Wason, JQ Zhang - World journal of cardiology, 2015 - ncbi.nlm.nih.gov
After myocardial infarction (MI), the heart undergoes extensive myocardial remodeling
through the accumulation of fibrous tissue in both the infarcted and noninfarcted …
through the accumulation of fibrous tissue in both the infarcted and noninfarcted …
Mitochondrial function in heart muscle from patients with idiopathic dilated cardiomyopathy
D Jarreta, J Orus, A Barrientos, O Miro… - Cardiovascular …, 2000 - academic.oup.com
Objective: To study the mitochondrial respiratory chain enzyme activities in patients with
idiopathic dilated cardiomyopathy (IDC). Methods: Mitochondrial respiratory chain enzyme …
idiopathic dilated cardiomyopathy (IDC). Methods: Mitochondrial respiratory chain enzyme …
[HTML][HTML] Uncovering sex-specific mechanisms of action of testosterone and redox balance
D Cruz-Topete, P Dominic, KY Stokes - Redox Biology, 2020 - Elsevier
The molecular and pharmacological manipulation of the endogenous redox system is a
promising therapy to limit myocardial damage after a heart attack; however, antioxidant …
promising therapy to limit myocardial damage after a heart attack; however, antioxidant …
Parkinson-susceptibility gene DJ-1/PARK7 protects the murine heart from oxidative damage in vivo
Oxidative stress is caused by an imbalance between the production of reactive oxygen
species (ROS) and the ability of an organism to eliminate these toxic intermediates …
species (ROS) and the ability of an organism to eliminate these toxic intermediates …
The oxidative stress hypothesis of congestive heart failure: radical thoughts
S Mak, GE Newton - Chest, 2001 - Elsevier
There is extensive experimental evidence from in vitro and animal experiments that
congestive heart failure (CHF) is a state of oxidative stress. Moreover, in animal models, the …
congestive heart failure (CHF) is a state of oxidative stress. Moreover, in animal models, the …