IL-6 and IL-8: an overview of their roles in healthy and pathological pregnancies

A Vilotić, M Nacka-Aleksić, A Pirković… - International journal of …, 2022 - mdpi.com
Interleukin-6 (IL-6) is an acknowledged inflammatory cytokine with a pleiotropic action,
mediating innate and adaptive immunity and multiple physiological processes, including …

Pre-eclampsia: its pathogenesis and pathophysiolgy: review articles

P Gathiram, J Moodley - Cardiovascular journal of Africa, 2016 - journals.co.za
Pre-eclampsia is a pregnancy-specific disorder that has a worldwide prevalence of 5-8%. It
is one of the main causes of maternal and perinatal morbidity and mortality globally and …

Maternal serum cytokine concentrations in healthy pregnancy and preeclampsia

T Spence, PJ Allsopp, AJ Yeates… - Journal of …, 2021 - Wiley Online Library
The maternal immune response is essential for successful pregnancy, promoting immune
tolerance to the fetus while maintaining innate and adaptive immunity. Uncontrolled …

Decreased maternal serum acetate and impaired fetal thymic and regulatory T cell development in preeclampsia

M Hu, D Eviston, P Hsu, E Mariño, A Chidgey… - Nature …, 2019 - nature.com
Maternal immune dysregulation seems to affect fetal or postnatal immune development.
Preeclampsia is a pregnancy-associated disorder with an immune basis and is linked to …

Mechanisms of endothelial dysfunction in pre-eclampsia and gestational diabetes mellitus: windows into future cardiometabolic health?

CJ McElwain, E Tuboly, FP McCarthy… - Frontiers in …, 2020 - frontiersin.org
Placental insufficiency and adipose tissue dysregulation are postulated to play key roles in
the pathophysiology of both pre-eclampsia (PE) and gestational diabetes mellitus (GDM). A …

Interleukin‐10: a pleiotropic regulator in pregnancy

SB Cheng, S Sharma - American Journal of Reproductive …, 2015 - Wiley Online Library
Pregnancy is a unique and well‐choreographed physiological process that involves intricate
interplay of inflammatory and anti‐inflammatory milieu, hormonal changes, and cellular and …

Disruption in the regulation of immune responses in the placental subtype of preeclampsia

J Geldenhuys, TM Rossouw, HA Lombaard… - Frontiers in …, 2018 - frontiersin.org
Preeclampsia is a pregnancy-specific disorder, of which one of its major subtypes, the
placental subtype is considered a response to an ischemic placental environment, impacting …

Immunological basis for recurrent fetal loss and pregnancy complications

H Deshmukh, SS Way - Annual Review of Pathology …, 2019 - annualreviews.org
Pregnancy stimulates an elaborate assortment of dynamic changes, allowing intimate
approximation of genetically discordant maternal and fetal tissues. Although the cellular and …

Inflammatory markers and preeclampsia: a systematic review

KD Black, JA Horowitz - Nursing research, 2018 - journals.lww.com
Background Preeclampsia (PE), a serious and variable pregnancy complication affecting
5%–10% of the obstetric population, has an undetermined etiology, yet inflammation is …

[PDF][PDF] Evaluation of levels of some inflammatory cytokines in preeclamptic women in owerri

OR Emeka-Obi, NC Ibeh, EI Obeagu… - Journal of …, 2021 - academia.edu
Preeclampsia is a serious and life-threatening pregnancy complication. In this study, the
levels of inflammatory cytokines were measured in preeclamptic women in Owerri, Imo …