Small molecule compounds with good anti-inflammatory activity reported in the literature from 01/2009 to 05/2021: A review
M Bian, Q Ma, Y Wu, H Du… - Journal of enzyme …, 2021 - Taylor & Francis
Inflammation and disease are closely related. Inflammation can induce various diseases,
and diseases can promote inflammatory response, and two possibly induces each other in a …
and diseases can promote inflammatory response, and two possibly induces each other in a …
The medicinal perspective of 2, 4‐thiazolidinediones based ligands as antimicrobial, antitumor and antidiabetic agents: A review
Thiazolidinedione (2, 4‐TZD), commonly known as glitazone, is a ubiquitous heterocyclic
pharmacophore possessing a plethora of pharmacological activities and offering a vast …
pharmacophore possessing a plethora of pharmacological activities and offering a vast …
Synthesis and biological evaluation of thiazolidine-2, 4-dione-pyrazole conjugates as antidiabetic, anti-inflammatory and antioxidant agents
A series of fourteen novel thiazolidine-2, 4-dione derivatives clubbed with pyrazole moiety
were synthesized via four step reaction procedure. Reactions were monitored by thin layer …
were synthesized via four step reaction procedure. Reactions were monitored by thin layer …
Coumarin-4-yl‐1, 2, 3‐triazol‐4-yl-methyl-thiazolidine-2, 4-diones: Synthesis, glucose uptake activity and cytotoxic evaluation
Thiazolidinedione (TZD) based medications have demonstrated to enhance the insulin
sensitivity control, hyperglycemia, and lipid metabolism in patients with type 2 diabetes …
sensitivity control, hyperglycemia, and lipid metabolism in patients with type 2 diabetes …
Synthesis, characterization, crystallographic, binding, in silico and antidiabetic studies of novel 2, 4-thiazolidinedione-phenothiazine molecular hybrids
MA Doddagaddavalli, VKA Kalalbandi… - Journal of Molecular …, 2023 - Elsevier
thiazolidinedione-phenothiazine molecular hybrids, 9a–9t were synthesized, characterized
and screened for antidiabetic activities viz., α-amylase inhibition and glucose uptake assay …
and screened for antidiabetic activities viz., α-amylase inhibition and glucose uptake assay …
Recent developments in the synthesis of N‐heterocyclic compounds as α‐amylase inhibitors via in‐vitro and in‐silico analysis: Future drugs for treating diabetes
In nature, N‐heterocyclic compounds and their derivatives are abundant. They serve as the
building blocks of many biological entities, such as enzymes, alkaloids, hormones …
building blocks of many biological entities, such as enzymes, alkaloids, hormones …
An insight into the synthesis and SAR of 2, 4-thiazolidinediones (2, 4-TZD) as multifunctional scaffold: a review
NS Sethi, DN Prasad, RK Singh - Mini Reviews in Medicinal …, 2020 - ingentaconnect.com
2, 4-Thiazolidinedione (2, 4-TZD) is a versatile pharmacophore, a privileged scaffold, and a
remarkable sulphur-containing heterocyclic compound with diverse pharmacological …
remarkable sulphur-containing heterocyclic compound with diverse pharmacological …
[HTML][HTML] New ibuprofen derivatives with thiazolidine-4-one scaffold with improved pharmaco-toxicological profile
Background Aryl-propionic acid derivatives with ibuprofen as representative drug are very
important for therapy, being recommended especially for anti-inflammatory and analgesic …
important for therapy, being recommended especially for anti-inflammatory and analgesic …
[HTML][HTML] Corrosion inhibition properties of thiazolidinedione derivatives for copper in 3.5 wt.% NaCl medium
Copper is the third-most-produced metal globally due to its exceptional mechanical and
thermal properties, among others. However, it suffers serious dissolution issues when …
thermal properties, among others. However, it suffers serious dissolution issues when …
Thiazolidinedione as a Promising Medicinal Scaffold for the Treatment of Type 2 Diabetes
G Singh, R Kumar, D DS, M Chaudhary… - Current Diabetes …, 2024 - ingentaconnect.com
Background: Thiazolidinediones, also known as glitazones, are considered as biologically
active scaffold and a well-established class of anti-diabetic agents for the treatment of type 2 …
active scaffold and a well-established class of anti-diabetic agents for the treatment of type 2 …