Foundation models for generalist medical artificial intelligence
The exceptionally rapid development of highly flexible, reusable artificial intelligence (AI)
models is likely to usher in newfound capabilities in medicine. We propose a new paradigm …
models is likely to usher in newfound capabilities in medicine. We propose a new paradigm …
Fast-track development of vaccines for SARS-CoV-2: the shots that saved the world
In December 2019, an outbreak emerged of severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) which leads to coronavirus disease 2019 (COVID-19). The World Health …
2 (SARS-CoV-2) which leads to coronavirus disease 2019 (COVID-19). The World Health …
Host traits shape virome composition and virus transmission in wild small mammals
YM Chen, SJ Hu, XD Lin, JH Tian, JX Lv, MR Wang… - Cell, 2023 - cell.com
Bats, rodents, and shrews are the most important animal sources of human infectious
diseases. However, the evolution and transmission of viruses among them remain largely …
diseases. However, the evolution and transmission of viruses among them remain largely …
Broad-spectrum pan-genus and pan-family virus vaccines
Although the development and clinical application of SARS-CoV-2 vaccines during the
COVID-19 pandemic demonstrated unprecedented vaccine success in a short time frame, it …
COVID-19 pandemic demonstrated unprecedented vaccine success in a short time frame, it …
Discovery and genomic characterization of a novel Henipavirus, Angavokely virus, from fruit bats in Madagascar
ABSTRACT The genus Henipavirus (family Paramyxoviridae) currently comprises seven
viruses, four of which have demonstrated prior evidence of zoonotic capacity. These include …
viruses, four of which have demonstrated prior evidence of zoonotic capacity. These include …
Henipavirus zoonosis: outbreaks, animal hosts and potential new emergence
H Li, JYV Kim, BS Pickering - Frontiers in microbiology, 2023 - frontiersin.org
Hendra virus (HeV) and Nipah virus (NiV) are biosafety level 4 zoonotic pathogens causing
severe and often fatal neurological and respiratory disease. These agents have been …
severe and often fatal neurological and respiratory disease. These agents have been …
Structure and design of Langya virus glycoprotein antigens
Z Wang, M McCallum, L Yan… - Proceedings of the …, 2024 - National Acad Sciences
Langya virus (LayV) is a recently discovered henipavirus (HNV), isolated from febrile
patients in China. HNV entry into host cells is mediated by the attachment (G) and fusion (F) …
patients in China. HNV entry into host cells is mediated by the attachment (G) and fusion (F) …
High‐Precision Synthesis of RNA‐Loaded Lipid Nanoparticles for Biomedical Applications
The recent development of RNA‐based therapeutics in delivering nucleic acids for gene
editing and regulating protein translation has led to the effective treatment of various …
editing and regulating protein translation has led to the effective treatment of various …
Henipaviruses: an expanding global public health concern?
J Quarleri, V Galvan, MV Delpino - Geroscience, 2022 - Springer
Abstract Nipah virus (NiV) and Hendra virus (HeV) are highly pathogenic zoonotic viruses of
the genus Henipavirus, family Paramyxoviridae that cause severe disease outbreaks in …
the genus Henipavirus, family Paramyxoviridae that cause severe disease outbreaks in …
Structure and antigenicity of divergent Henipavirus fusion glycoproteins
A Isaacs, YS Low, KL Macauslane, J Seitanidou… - Nature …, 2023 - nature.com
In August 2022, a novel henipavirus (HNV) named Langya virus (LayV) was isolated from
patients with severe pneumonic disease in China. This virus is closely related to Mòjiāng …
patients with severe pneumonic disease in China. This virus is closely related to Mòjiāng …