Iodothyronine deiodinases (DIO) are a family of selenoproteins controlling systemic and
local availability of the major thyroid hormone l-thyroxine (T4), a prohormone secreted by the …

The maintenance of energy balance is regulated by complex homeostatic mechanisms,
including those emanating from adipose tissue. The main function of the adipose tissue is to …

Background: An in-depth understanding of the fundamental principles that regulate thyroid
hormone homeostasis is critical for the development of new diagnostic and treatment …

The processes and pathways mediating the intermediary metabolism of carbohydrates,
lipids, and proteins are all affected by thyroid hormones (THs) in almost all tissues. Particular …

Thyroid hormones act as pleiotropic factors in many tissues during development, by
regulating genes involved in differentiation. The adipose tissue, a target of thyroid …

Brown adipose tissue (BAT) thermogenesis increases when uncoupling protein-1 (UCP1) is
activated adrenergically and requires T3. In humans, UCP1 activation in BAT seems …

Thyroid hormone (TH) is crucial for development and metabolism of many tissues. The
physiological relevance and therapeutic potential of TH analogs have gained attention in the …

Thyroid hormones (TH s) are essential for the regulation of development and metabolism in
key organs. TH s produce biological effects both by directly affecting gene expression …

Iodine is a highly reactive element with a single natural and stable isotopic form (127I). In the
biosphere, it is one of the 30 essential elements for life, and its chemical speciation defines …

This work contains a comparison between variational integrators and energy-momentum
schemes for flexible multibody dynamics. In this connection, a specific “rotationless” …