Inflammation and tumor progression: signaling pathways and targeted intervention

H Zhao, L Wu, G Yan, Y Chen, M Zhou… - Signal transduction and …, 2021 - nature.com
Cancer development and its response to therapy are regulated by inflammation, which
either promotes or suppresses tumor progression, potentially displaying opposing effects on …

Role of pyroptosis in cardiovascular disease

Z Zhaolin, L Guohua, W Shiyuan, W Zuo - Cell proliferation, 2019 - Wiley Online Library
Cardiac function is determined by the dynamic equilibrium of various cell types and the
extracellular matrix that composes the heart. Cardiovascular diseases (CVDs), especially …

Tumour-associated macrophages: versatile players in the tumour microenvironment

ZZ Ji, MKK Chan, ASW Chan, KT Leung… - Frontiers in Cell and …, 2023 - frontiersin.org
Tumour-Associated Macrophages (TAMs) are one of the pivotal components of the tumour
microenvironment. Their roles in the cancer immunity are complicated, both pro-tumour and …

Type I interferon production of plasmacytoid dendritic cells under control

D Bencze, T Fekete, K Pázmándi - International journal of molecular …, 2021 - mdpi.com
One of the most powerful and multifaceted cytokines produced by immune cells are type I
interferons (IFNs), the basal secretion of which contributes to the maintenance of immune …

Neuroinflammatory gene expression analysis reveals pathways of interest as potential targets to improve the recording performance of intracortical microelectrodes

S Song, B Regan, ES Ereifej, ER Chan, JR Capadona - Cells, 2022 - mdpi.com
Intracortical microelectrodes are a critical component of brain-machine interface (BMI)
systems. The recording performance of intracortical microelectrodes used for both basic …

NLRX1 is a multifaceted and enigmatic regulator of immune system function

MA Nagai-Singer, HA Morrison, IC Allen - Frontiers in Immunology, 2019 - frontiersin.org
Over the last decade, significant progress has been achieved in defining mechanisms
underlying NLR regulation of immune system function. However, several NLR family …

NLRC3 expression in dendritic cells attenuates CD4+ T cell response and autoimmunity

Y Fu, X Zhan, Y Wang, X Jiang, M Liu, Y Yang… - The EMBO …, 2019 - embopress.org
NOD‐like receptor (NLR) family CARD domain containing 3 (NLRC 3), an intracellular
member of NLR family, is a negative regulator of inflammatory signaling pathways in innate …

The lncRNAs involved in regulating the RIG-I signaling pathway

J Liu, Q Ji, F Cheng, D Chen, T Geng… - Frontiers in Cellular …, 2022 - frontiersin.org
Understanding the targets and interactions of long non-coding RNAs (lncRNAs) related to
the retinoic acid-inducible gene-I (RIG-I) signaling pathway is essential for developing …

Gut microbiota and immunotherapy for Alzheimer's disease

CL Dai, F Liu, K Iqbal, CX Gong - International Journal of Molecular …, 2022 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that eventually leads
to dementia and death of the patient. Currently, no effective treatment is available that can …

Role of NLRs in the regulation of type I interferon signaling, host defense and tolerance to inflammation

I Kienes, T Weidl, N Mirza, M Chamaillard… - International Journal of …, 2021 - mdpi.com
Type I interferon signaling contributes to the development of innate and adaptive immune
responses to either viruses, fungi, or bacteria. However, amplitude and timing of the …