Inflammation and tumor progression: signaling pathways and targeted intervention
H Zhao, L Wu, G Yan, Y Chen, M Zhou… - Signal transduction and …, 2021 - nature.com
Cancer development and its response to therapy are regulated by inflammation, which
either promotes or suppresses tumor progression, potentially displaying opposing effects on …
either promotes or suppresses tumor progression, potentially displaying opposing effects on …
Role of pyroptosis in cardiovascular disease
Z Zhaolin, L Guohua, W Shiyuan, W Zuo - Cell proliferation, 2019 - Wiley Online Library
Cardiac function is determined by the dynamic equilibrium of various cell types and the
extracellular matrix that composes the heart. Cardiovascular diseases (CVDs), especially …
extracellular matrix that composes the heart. Cardiovascular diseases (CVDs), especially …
Tumour-associated macrophages: versatile players in the tumour microenvironment
ZZ Ji, MKK Chan, ASW Chan, KT Leung… - Frontiers in Cell and …, 2023 - frontiersin.org
Tumour-Associated Macrophages (TAMs) are one of the pivotal components of the tumour
microenvironment. Their roles in the cancer immunity are complicated, both pro-tumour and …
microenvironment. Their roles in the cancer immunity are complicated, both pro-tumour and …
Type I interferon production of plasmacytoid dendritic cells under control
D Bencze, T Fekete, K Pázmándi - International journal of molecular …, 2021 - mdpi.com
One of the most powerful and multifaceted cytokines produced by immune cells are type I
interferons (IFNs), the basal secretion of which contributes to the maintenance of immune …
interferons (IFNs), the basal secretion of which contributes to the maintenance of immune …
Neuroinflammatory gene expression analysis reveals pathways of interest as potential targets to improve the recording performance of intracortical microelectrodes
Intracortical microelectrodes are a critical component of brain-machine interface (BMI)
systems. The recording performance of intracortical microelectrodes used for both basic …
systems. The recording performance of intracortical microelectrodes used for both basic …
NLRX1 is a multifaceted and enigmatic regulator of immune system function
Over the last decade, significant progress has been achieved in defining mechanisms
underlying NLR regulation of immune system function. However, several NLR family …
underlying NLR regulation of immune system function. However, several NLR family …
NLRC3 expression in dendritic cells attenuates CD4+ T cell response and autoimmunity
Y Fu, X Zhan, Y Wang, X Jiang, M Liu, Y Yang… - The EMBO …, 2019 - embopress.org
NOD‐like receptor (NLR) family CARD domain containing 3 (NLRC 3), an intracellular
member of NLR family, is a negative regulator of inflammatory signaling pathways in innate …
member of NLR family, is a negative regulator of inflammatory signaling pathways in innate …
The lncRNAs involved in regulating the RIG-I signaling pathway
J Liu, Q Ji, F Cheng, D Chen, T Geng… - Frontiers in Cellular …, 2022 - frontiersin.org
Understanding the targets and interactions of long non-coding RNAs (lncRNAs) related to
the retinoic acid-inducible gene-I (RIG-I) signaling pathway is essential for developing …
the retinoic acid-inducible gene-I (RIG-I) signaling pathway is essential for developing …
Gut microbiota and immunotherapy for Alzheimer's disease
CL Dai, F Liu, K Iqbal, CX Gong - International Journal of Molecular …, 2022 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that eventually leads
to dementia and death of the patient. Currently, no effective treatment is available that can …
to dementia and death of the patient. Currently, no effective treatment is available that can …
Role of NLRs in the regulation of type I interferon signaling, host defense and tolerance to inflammation
I Kienes, T Weidl, N Mirza, M Chamaillard… - International Journal of …, 2021 - mdpi.com
Type I interferon signaling contributes to the development of innate and adaptive immune
responses to either viruses, fungi, or bacteria. However, amplitude and timing of the …
responses to either viruses, fungi, or bacteria. However, amplitude and timing of the …