Myokines are muscle‐derived cytokines and chemokines that act extensively on organs and
exert beneficial metabolic functions in the whole‐body through specific signal networks …

Fibroblast growth factors (FGFs) and their receptors (FGFRs) are expressed throughout all
stages of skeletal development. In the limb bud and in cranial mesenchyme, FGF signaling …

Abstract Purpose of Review In perilacunar/canalicular remodeling (PLR), osteocytes
dynamically resorb, and then replace, the organic and mineral components of the …

Abstract Purpose of Review The purpose of this review is to discuss the molecular
mechanisms involved in osteocyte dendrite formation, summarize the similarities between …

Irradiation‑induced bone remodeling imbalances arise as a consequence of the
dysregulation of bone formation and resorption. Due to the abundance of osteocytes, their …

Irradiation‐induced bone loss is widely reported, especially in radiotherapy‐induced
osteoporosis. In addition to the mechanism of osteogenesis inhibition and …

Ligament/tendon and cartilage injuries are clinically common diseases that perplex most
clinicians. Because of the lack of blood vessels and nerves, their self-repairing abilities are …

Background Osteoporosis (OP) is a prevalent disorder characterized by the loss of bone
mass and the deterioration of bone microarchitecture. OP is attributed to various factors …

Lysophosphatidic acid (LPA) is a natural bioactive phospholipid with pleiotropic activities
affecting multiple tissues, including bone. LPA exerts its biological functions by binding to G …

Pediatric renal osteodystrophy is characterized by skeletal mineralization defects, but the
role of osteoblast and osteocyte maturation in the pathogenesis of these defects is unknown …