Numerous reports of vascular events after an initial recovery from COVID-19 form our
impetus to investigate the impact of COVID-19 on vascular health of recovered patients. We …

Apicomplexan parasites have complex metabolic networks that coordinate acquisition of
metabolites by de novo synthesis and by scavenging from the host. Toxoplasma gondii has …

Toxoplasma gondii is a human pathogen prevalent worldwide that poses a challenging and
unmet need for novel treatment of toxoplasmosis. Using a semi-automated reconstruction …

Human coronaviruses represent a significant disease burden; however, there is currently no
antiviral strategy to combat infection. The outbreak of severe acute respiratory syndrome …

Clostridium thermocellum is a promising candidate for consolidated bioprocessing because
it can directly ferment cellulose to ethanol. Despite significant efforts, achieved yields and …

Identification of drug target in protozoan T. gondii is an important step in the development of
chemotherapeutic agents. Likewise, exploring phytochemical compounds effective against …

Isolation, screening and in vivo assays have been used for evaluating anti-diarrhea
bioactive of Alpinia oxyphylla. Preliminary experimental results showed that 95% ethanol …

Background Increasing resistance to anti-tuberculosis drugs has driven the need for
developing new drugs. Resources such as the tropical disease research (TDR) target …

Accurate prediction of ligand-binding poses is crucial for understanding molecular
interactions and is very important for drug discovery, structural design, and optimization. In …

hydroxypanduratin A is a secondary metabolite of Boesenbergia pandurata
Schult.(Fingerroot) plant with various pharmacological activities such as neuroprotective …