Ultrasonic neuromodulation is a rapidly growing field, in which low-intensity ultrasound (US)
is delivered to nervous system tissue, resulting in transient modulation of neural activity. This …

Brain temperature, as an independent therapeutic target variable, has received increasingly
intense clinical attention. To date, brain hypothermia represents the most potent …

Despite the increasing use of optogenetics in vivo, the effects of direct light exposure to brain
tissue are understudied. Of particular concern is the potential for heat induced by prolonged …

We investigated the role of astrocytes in activity-dependent modulation of inhibitory synaptic
transmission in hippocampal slices. Repetitive firing of an interneuron decreased the …

Many complex behaviours, like speech or music, have a hierarchical organization with
structure on many timescales, but it is not known how the brain controls the timing of …

Neuronal control with high temporal precision is possible with optogenetics, yet currently
available methods do not enable to control independently multiple locations in the brains of …

Sensory acuity and motor dexterity deteriorate when human limbs cool down, but pain
perception persists and cold-induced pain can become excruciating. Evolutionary pressure …

Physiological body temperature is an important determinant for neural functions, and it is
well established that changes in temperature have dynamic influences on hippocampal …

1. In hippocampal pyramidal cells, action potentials are followed by three after‐
hyperpolarizations (AHPs): a fast AHP (fAHP) lasting 2‐5 ms, a medium AHP (mAHP) lasting …

Focused ultrasound (FUS) neuromodulation has shown that mechanical waves can interact
with cell membranes and mechanosensitive ion channels, causing changes in neuronal …