Tumor immunology and tumor evolution: intertwined histories

J Galon, D Bruni - Immunity, 2020 - cell.com
Cancer is a complex disease whose outcome depends largely on the cross-talk between the
tumor and its microenvironment. Here, we review the evolution of the field of tumor …

Natural killer cell therapy for hematologic malignancies: successes, challenges, and the future

MG Lamb, HG Rangarajan, BP Tullius… - Stem Cell Research & …, 2021 - Springer
The adoptive transfer of natural killer (NK) cells is an emerging therapy in the field of
immuno-oncology. In the last 3 decades, NK cells have been utilized to harness the anti …

Haploidentical vs sibling, unrelated, or cord blood hematopoietic cell transplantation for acute lymphoblastic leukemia

MJ Wieduwilt, L Metheny III, MJ Zhang… - Blood …, 2022 - ashpublications.org
The role of haploidentical hematopoietic cell transplantation (HCT) using posttransplant
cyclophosphamide (PTCy) for acute lymphoblastic leukemia (ALL) is being defined. We …

A comprehensive model to predict severe acute graft-versus-host disease in acute leukemia patients after haploidentical hematopoietic stem cell transplantation

MZ Shen, SD Hong, R Lou, RZ Chen, XH Zhang… - … hematology & oncology, 2022 - Springer
Background Acute graft-versus-host disease (aGVHD) remains the major cause of early
mortality after haploidentical related donor (HID) hematopoietic stem cell transplantation …

Efficacy and safety of ruxolitinib in steroid-refractory graft-versus-host disease: A meta-analysis

S Fan, WX Huo, Y Yang, MZ Shen, XD Mo - Frontiers in immunology, 2022 - frontiersin.org
Ruxolitinib is an important treatment for steroid refractory graft-versus-host disease (SR-
GVHD). Therefore, we reported the updated results of a systematic review and meta …

In-vivo T-cell depleted reduced-intensity conditioned allogeneic haematopoietic stem-cell transplantation for patients with acute lymphoblastic leukaemia in first …

DI Marks, L Clifton-Hadley, M Copland… - The Lancet …, 2022 - thelancet.com
Background The outcome of chemotherapy in patients older than 40 years with acute
lymphoblastic leukaemia is poor and myeloablative allogeneic haematopoietic stem-cell …

Effect of graft-versus-host disease on outcomes of HLA-haploidentical peripheral blood transplantation using post-transplant cyclophophamide

Y Shimomura, S Komukai, T Kitamura… - Bone Marrow …, 2024 - nature.com
There is limited evidence regarding the association between graft-versus-host disease
(GVHD) and reduced relapse in patients who undergo allogeneic hematopoietic stem cell …

Impact of a novel prognostic model on allogeneic hematopoietic stem cell transplantation outcomes in patients with CMML

JY Zhou, S Wang, HL Yuan, YJ Xu… - American Journal of …, 2023 - Wiley Online Library
Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic stem cell malignancy,
and allogeneic hematopoietic stem cell transplantation (allo‐HSCT) is the only curable …

Incidence, clinical presentation, risk factors, outcomes, and biomarkers in de novo late acute GVHD

Y Akahoshi, N Spyrou, WJ Hogan, F Ayuk… - Blood …, 2023 - ashpublications.org
Late acute graft-versus-host disease (GVHD) is defined as de novo acute GVHD presenting
beyond 100 days after allogeneic hematopoietic cell transplantation (HCT) without …

CMV reactivation after allogeneic HCT is associated with a reduced risk of relapse in acute lymphoblastic leukemia

Y Akahoshi, H Nakasone, K Takenaka… - Blood …, 2023 - ashpublications.org
Cytomegalovirus reactivation (CMVR) after allogeneic hematopoietic cell transplantation
(HCT) is a frequent complication related to survival outcomes; however, its impact on …