A critical appraisal of the relative contribution of tissue architecture, genetics, epigenetics and cell metabolism to carcinogenesis
TW Grunt, G Heller - Progress in Biophysics and Molecular Biology, 2023 - Elsevier
Here we contrast several carcinogenesis models. The somatic-mutation-theory posits
mutations as main causes of malignancy. However, inconsistencies led to alternative …
mutations as main causes of malignancy. However, inconsistencies led to alternative …
MEK/ERK and PI3K/AKT pathway inhibitors affect the transformation of myelodysplastic syndrome into acute myeloid leukemia via H3K27me3 methylases and de …
Z Zheng, X Chen, Y Zhang… - … Journal of Oncology, 2023 - spandidos-publications.com
The transformation of myelodysplastic syndrome (MDS) into acute myeloid leukemia (AML)
poses a significant clinical challenge. The trimethylation of H3 on lysine 27 (H3K27me3) …
poses a significant clinical challenge. The trimethylation of H3 on lysine 27 (H3K27me3) …
Lenalidomide and eltrombopag for treatment of low-or intermediate-risk myelodysplastic syndrome: result of a phase II clinical trial
JD Gonzalez-Lugo, S Kambhampati, A Yacoub… - Clinical Cancer …, 2023 - AACR
Purpose: Thrombocytopenia is a serious complication of myelodysplastic syndromes (MDS)
associated with an increased bleeding risk and worse prognosis. Eltrombopag (ELT), a …
associated with an increased bleeding risk and worse prognosis. Eltrombopag (ELT), a …
An interactive mass spectrometry atlas of histone posttranslational modifications in T-cell acute leukemia
L Provez, B Van Puyvelde, L Corveleyn… - Scientific data, 2022 - nature.com
The holistic nature of omics studies makes them ideally suited to generate hypotheses on
health and disease. Sequencing-based genomics and mass spectrometry (MS)-based …
health and disease. Sequencing-based genomics and mass spectrometry (MS)-based …
[HTML][HTML] 表观遗传学治疗在急性髓系白血病中的研究进展
杨香会， 付滕， 张海亚， 王彦丽， 李丽… - Advances in Clinical …, 2022 - hanspub.org
急性髓系白血病(acute myeloid leukemia, AML) 是一种高度异质性的血液系统恶性肿瘤,
为造血干细胞的克隆性疾病. 近年来, 随着对表观遗传学机制及分子靶向药物的深入研究和临床 …
为造血干细胞的克隆性疾病. 近年来, 随着对表观遗传学机制及分子靶向药物的深入研究和临床 …
[PDF][PDF] an interactive mass spectrometry atlas of histone posttranslational modifications in T-cell acute leukemia
The holistic nature of omics studies makes them ideally suited to generate hypotheses on
health and disease. Sequencing-based genomics and mass spectrometry (MS)-based …
health and disease. Sequencing-based genomics and mass spectrometry (MS)-based …
Hoạt tính gây độc tế bào ung thư máu của dịch chiết cây vối thuốc schima wallichii thu hái ở Quảng Trị
NY Nhi, TTT Linh, VTL Mỹ, TTP May, PTV Phú… - Tạp chí Khoa học và …, 2022 - jst-ud.vn
Tóm tắt Trong quá trình tìm kiếm các thực vật tự nhiên để hỗ trợ điều trị ung thư, nhóm tác
giả đã phát hiện ra dịch chiết cồn của Vối thuốc Schima wallichii họ Chè Theacea ở Quảng …
giả đã phát hiện ra dịch chiết cồn của Vối thuốc Schima wallichii họ Chè Theacea ở Quảng …