Mitochondria are organelles that are able to adjust and respond to different stressors and
metabolic needs within a cell, showcasing their plasticity and dynamic nature. These …

Patients with heart failure (HF) and their families experience stress and suffering from a
variety of sources over the course of the HF experience. Palliative care is an interdisciplinary …

Contrary to common perception, modern palliative care (PC) is applicable to all people with
an incurable disease, not only cancer. PC is appropriate at every stage of disease …

Atherosclerosis is one of the most fatal diseases in the world. The associated thickening of
the arterial wall and its background and consequences make it a very composite disease …

Symptoms of cardiovascular disease drive health care use and are a major contributor to
quality of life. Symptoms are of fundamental significance not only to the diagnosis of …

Background Optimally treated heart failure (HF) patients often have persisting symptoms and
poor health-related quality of life. Comorbidities are common, but little is known about their …

Activation of the renin-angiotensin system (RAS) is associated with hypertension and heart
disease. However, how RAS activation causes cardiac lesions remains elusive. Here we …

Background Traditional clinical trials require tests and procedures that are administered in
centralized clinical research sites, which are beyond the standard of care that patients …

Introduction/Objective: This review aimed to summarize articles describing caregiver burden
and the relationship between health outcomes as well as describing interventions focusing …

Chronic heart failure (CHF) is a chronic, progressive disease that has detrimental
consequences on a patient's quality of life (QoL). In part due to requirements for market …