Advances in membrane-based chiral separation

C Yu, BH Yin, Y Wang, S Luo, X Wang - Coordination Chemistry Reviews, 2023 - Elsevier
Chiral separation is essential in discovering bioactive substances because the enantiomer
of chiral drugs usually exhibits different or even opposite biological activity and toxicity. As a …

Structure control of polysaccharide derivatives for efficient separation of enantiomers by chromatography

T Ikai, Y Okamoto - Chemical Reviews, 2009 - ACS Publications
Chirality is a ubiquitous feature in living systems. Today, it is widely recognized that many
biologically interesting compounds, such as drugs, agrochemicals, food additives, and …

Engineering chiral porous metal-organic frameworks for enantioselective adsorption and separation

Y Peng, T Gong, K Zhang, X Lin, Y Liu, J Jiang… - Nature …, 2014 - nature.com
The separation of racemic molecules is of substantial significance not only for basic science
but also for technical applications, such as fine chemicals and drug development. Here we …

The chiral nano-world: chiroptically active quantum nanostructures

FP Milton, J Govan, MV Mukhina, YK Gun'ko - Nanoscale Horizons, 2016 - pubs.rsc.org
Chirality is one of the key factors in molecular recognition, therefore the development of new
chiral nanoparticles is of great interest to many fields of scientific endeavour including …

Identifying a hidden conglomerate chiral pool in the CSD

MP Walsh, JA Barclay, CS Begg, J Xuan, NT Johnson… - JACS Au, 2022 - ACS Publications
Conglomerate crystallization is the spontaneous generation of individually enantioenriched
crystals from a nonenantioenriched material. This behavior is responsible for spontaneous …

Enhanced direct crystallization resolution of racemates mediated in chiral ionic liquid cosolvent mixtures: experimental, statistical, and QM simulation studies

X Qin, Y Xu, B Lou, C Liu, L Zhang, X Liu… - Crystal Growth & …, 2023 - ACS Publications
Four chiral ionic liquids (CILs) of 1-hexyl-3-methylimidazolium-l-2-aminobutyrate ([Hmim][l-2-
AbA]), 1-hexyl-3-methylimidazolium-d-2-aminobutyrate ([Hmim][d-2-AbA]), di-1-hexyl-3 …

Developments in the catalytic asymmetric synthesis of agrochemicals and their synthetic importance

SK Sharma, ASR Paniraj… - Journal of Agricultural and …, 2021 - ACS Publications
Catalytic asymmetric synthesis has become an essential tool for the enantioselective
synthesis of pharmaceuticals, natural products, and agrochemicals (mainly fungicides …

Effect of stereogenic centers on the self-sorting, depolymerization, and atropisomerization kinetics of porphyrin-based aggregates

F Helmich, MMJ Smulders, CC Lee… - Journal of the …, 2011 - ACS Publications
We present our results on the mixing of different porphyrin molecules in supramolecular
assemblies. Herein, chiral amplification experiments reveal the subtle role of the structural …

Effect of additives on preferential crystallization for the chiral resolution of citrulline: experimental, statistical, and molecular dynamics simulation studies

L Zhang, Y Xu, B Lou, X Qin, L Zhang, X Liu… - Crystal Growth & …, 2022 - ACS Publications
The molar fraction solubilities of l-, d-, and dl-citrulline were first determined in aqueous
solutions with different concentrations of (R)-1, 3-butanediol from 283.15 to 328.15 K under …

Completely chiral optical force for enantioseparation

ID Rukhlenko, NV Tepliakov, AS Baimuratov… - Scientific reports, 2016 - nature.com
Fast and reliable separation of enantiomers of chiral nanoparticles requires elimination of all
the forces that are independent of the nanoparticle handedness and creation of a sufficiently …