Herpes simplex virus (HSV) establishes a latent infection in peripheral neurons and can
periodically reactivate to cause disease. Reactivation can be triggered by a variety of stimuli …

Herpes simplex virus type 1 (HSV-1), a neurotropic herpes virus, is able to establish a
lifelong latent infection in the human host. Following primary replication in mucosal epithelial …

Current treatments for advanced hepatocellular carcinoma (HCC) have limited success in
improving patients' quality of life and prolonging life expectancy. The clinical need for more …

ABSTRACT Herpes simplex virus-1 (HSV-1) establishes a latent infection in peripheral
neurons and periodically reactivates to permit transmission, which can result in clinical …

Viruses encode for structural proteins that participate in virion formation and include capsid
and envelope proteins. In addition, viruses encode for an array of non-structural accessory …

Despite some promising results, the majority of patients do not benefit from T cell therapies,
as tumors prevent T cells from entering the tumor, shut down their activity, or downregulate …

Herpes simplex virus type 1 (HSV-1) is a common virus of mankind and HSV-1 infections are
a significant cause of blindness. The current antiviral treatment of herpes infection relies on …

Neuron-virus interactions that occur during herpes simplex virus (HSV) infection are not fully
understood. Neurons are the site of lifelong latency and are a crucial target for long-term …

Exosomes are membrane-bound vesicles of endocytic origin, secreted into the extracellular
milieu, in which various biological components such as proteins, nucleic acids, and lipids …

Herpes simplex virus (HSV) infection relies on immediate early proteins that initiate viral
replication. Among them, ICP0 is known, for many years, to facilitate the onset of viral gene …