Anticancer half-sandwich rhodium (III) complexes

K Máliková, L Masaryk, P Štarha - Inorganics, 2021 - mdpi.com
Platinum-based anticancer drugs are most likely the most successful group of bioinorganic
compounds. Their apparent disadvantages have led to the development of anticancer …

Binding mechanisms of half-sandwich Rh (III) and Ru (II) arene complexes on human serum albumin: A comparative study

O Dömötör, ÉA Enyedy - JBIC Journal of Biological Inorganic Chemistry, 2019 - Springer
Various half-sandwich ruthenium (II) arene complexes and rhodium (III) arene complexes
have been intensively investigated due to their prominent anticancer activity. The interaction …

Anticancer organorhodium and-iridium complexes with low toxicity in vivo but high potency in vitro: DNA damage, reactive oxygen species formation, and haemolytic …

S Parveen, M Hanif, E Leung, KKH Tong… - Chemical …, 2019 - pubs.rsc.org
Redox-modulating anticancer drugs allow the exploitation of altered redox biology observed
in many cancer cells. We discovered dinuclear RhIII (Cp*) and IrIII (Cp*) complexes that …

Diversity in the Interaction of Amino Acid-and Peptide-Based Hydroxamic Acids with Some Platinum Group Metals in Solution

L Bíró, P Buglyó, E Farkas - Molecules, 2022 - mdpi.com
Complexes that incorporate both ligand (s) and metal (s) exhibiting cytotoxic activity can
especially be interesting to develop multifunctional drug molecules with desired activities. In …

Half-sandwich organometallic Ru and Rh complexes of (N, N) donor compounds: Effect of ligand methylation on solution speciation and anticancer activity

JP Mészáros, VFS Pape, G Szakács, G Németi… - Dalton …, 2021 - pubs.rsc.org
A series of half-sandwich polypyridyl complexes was synthesized and compared focusing
on structural, cytotoxic and aqueous solution behaviour. The formula of the synthesized …

Critical factors affecting the albumin binding of half-sandwich Ru (II) and Rh (III) complexes of 8-hydroxyquinolines and oligopyridines

O Dömötör, T Pivarcsik, JP Mészáros, I Szatmári… - Dalton …, 2021 - pubs.rsc.org
There is significant interest today in the interaction of half-sandwich anticancer
organometallic complexes with proteins. It is considered as a crucial factor in the transport …

An 8-hydroxyquinoline–proline hybrid with multidrug resistance reversal activity and the solution chemistry of its half-sandwich organometallic Ru and Rh complexes

JP Mészáros, JM Poljarević, I Szatmári, O Csuvik… - Dalton …, 2020 - pubs.rsc.org
Herein the design and synthesis of a new 8-hydroxyquinoline derivative,(S)-5-chloro-7-
((proline-1-yl) methyl) 8-hydroxyquinoline (HQCl-Pro), with good water solubility and …

Comparative solution equilibrium studies of antitumor ruthenium (η 6-p-cymene) and rhodium (η 5-C 5 Me 5) complexes of 8-hydroxyquinolines

O Dömötör, VFS Pape, NV May, G Szakács… - Dalton …, 2017 - pubs.rsc.org
Complex formation processes of [Ru (η6-p-cymene)(H2O) 3]+ and [Rh (η5-C5Me5)(H2O)
3]+ organometallic cations with 8-hydroxyquinoline (HQ) ligands were studied in aqueous …

Cytotoxic half-sandwich Rh (III) and Ir (III) β-diketonates

A Petrini, R Pettinari, F Marchetti, C Pettinari… - Inorganic …, 2017 - ACS Publications
A series of half-sandwich pentamethylcyclopentadienyl rhodium (III) and iridium (III)
complexes [Cp* M (DBM/HDB/AVB) Cl] and [Cp* M (DBM/HDB/AVB)(PTA)][SO3CF3], where …

Thiomaltol‐Based Organometallic Complexes with 1‐Methylimidazole as Leaving Group: Synthesis, Stability, and Biological Behavior

CM Hackl, MS Legina, V Pichler… - … A European Journal, 2016 - Wiley Online Library
Thiomaltol, a potential S, O‐coordinating molecule, has been utilized for the complexation of
four different organometallic fragments, yielding the desired RuII, OsII, RhIII, and IrIII …