The nuclear factor-kappaB (NF-κB) signaling pathway is considered as a potential
therapeutic target in cancer therapy. It has been well established that transcription factor NF …

Pancreatic cancer is the deadliest disease, with a five-year overall survival rate of just 11%.
The pancreatic cancer patients diagnosed with early screening have a median overall …

Since the initial work, a decade ago that the combination of C-reactive protein and albumin,
the Glasgow Prognostic Score (GPS), had independent prognostic value in patients with …

Cancer remains a leading causes of death worldwide and an elevated systemic
inflammatory response (SIR) is associated with reduced survival in patients with operable …

Pancreatic ductal adenocarcinoma (PDAC) is one of the leading causes of cancer‐related
mortality. Despite significant advances made in the treatment of other cancers, current …

Perioperative adjuvant treatment and complete resection is the standard treatment for
resectable pancreatic cancer and systemic chemotherapy is standard treatment for …

Objectives To assess the impact of neural invasion/NI on overall survival/OS and tumor
recurrence in pancreatic ductal adenocarcinoma/PDAC. Summary background data NI is a …

Background Oesophageal adenocarcinoma (OAC) is increasingly common in the west, and
survival remains poor at 10–15% at 5 years. Immune responses are increasingly implicated …

Background We studied the prognostic effect of CD3-, CD8-and CD103-positive T
lymphocytes in a cohort of 165 patients with resected pancreatic ductal adenocarcinomas …

The molecular mechanism of perineural invasion (PNI) is unclear, and insufficient detection
during early-stage PNI in vivo hampers its investigation. We aimed to identify a cytokine …