[HTML][HTML] Mitochondria on the move: Horizontal mitochondrial transfer in disease and health

LF Dong, J Rohlena, R Zobalova, Z Nahacka… - Journal of Cell …, 2023 - rupress.org
Mammalian genes were long thought to be constrained within somatic cells in most cell
types. This concept was challenged recently when cellular organelles including …

Traveling with purpose: cell-to-cell transport of plant mRNAs

M Kitagawa, TM Tran, D Jackson - Trends in Cell Biology, 2024 - cell.com
Messenger RNAs (mRNAs) in multicellular organisms can act as signals transported cell-to-
cell and over long distances. In plants, mRNAs traffic cell-to-cell via plasmodesmata (PDs) …

Tunneling nanotubes, TNT, communicate glioblastoma with surrounding non-tumor astrocytes to adapt them to hypoxic and metabolic tumor conditions

S Valdebenito, S Malik, R Luu, O Loudig, M Mitchell… - Scientific reports, 2021 - nature.com
Cell-to-cell communication is essential for the development and proper function of
multicellular systems. We and others demonstrated that tunneling nanotubes (TNT) …

Horizontal gene transfer in eukaryotes: aligning theory with data

PJ Keeling - Nature Reviews Genetics, 2024 - nature.com
Horizontal gene transfer (HGT), or lateral gene transfer, is the non-sexual movement of
genetic information between genomes. It has played a pronounced part in bacterial and …

Tunneling nanotube-mediated communication: a mechanism of intercellular nucleic acid transfer

J Driscoll, P Gondaliya, T Patel - International journal of molecular …, 2022 - mdpi.com
Tunneling nanotubes (TNTs) are thin, F-actin-based membranous protrusions that connect
distant cells and can provide ea novel mechanism for intercellular communication. By …

Extracellular vesicle RNA signaling in the liver tumor microenvironment

P Gondaliya, AA Sayyed, J Driscoll, K Patel, T Patel - Cancer letters, 2023 - Elsevier
The tumor microenvironment (TME) in liver cancers such as hepatocellular cancer (HCC)
consists of a complex milieu of liver tissue-resident cells, infiltrated immune cells, and …

Tunneling Nanotube: An Enticing Cell–Cell Communication in the Nervous System

S Dagar, S Subramaniam - Biology, 2023 - mdpi.com
Simple Summary This review highlights the role of tunneling nanotubes (TNTs) and TNT-like
structures in the nervous system. TNTs are thin, hollow plasma membrane projections that …

Global analysis of contact-dependent human-to-mouse intercellular mRNA and lncRNA transfer in cell culture

S Dasgupta, DY Dayagi, G Haimovich, E Wyler… - Elife, 2023 - elifesciences.org
Full-length mRNAs transfer between adjacent mammalian cells via direct cell-to-cell
connections called tunneling nanotubes (TNTs). However, the extent of mRNA transfer at the …

Membrane interaction to intercellular spread of pathology in Alzheimer's disease

DK Valappil, NJ Mini, A Dilna, S Nath - Frontiers in Neuroscience, 2022 - frontiersin.org
Progressive development of pathology is one of the major characteristic features of
neurodegenerative diseases. Alzheimer's disease (AD) is the most prevalent among them …

Horizontal MicroRNA transfer by platelets–evidence and implications

M Mussbacher, A Pirabe, L Brunnthaler… - Frontiers in …, 2021 - frontiersin.org
For decades, platelets have been known for their central role in hemostasis and their ability
to release bioactive molecules, allowing inter-platelet communication and crosstalk with the …