We review theoretical and numerical models of the glymphatic system, which circulates
cerebrospinal fluid and interstitial fluid around the brain, facilitating solute transport. Models …

Circulation of cerebrospinal fluid and interstitial fluid around the central nervous system and
through the brain transports not only those water-like fluids but also any solutes they carry …

We introduce and analyze a discontinuous Galerkin method for the numerical modeling of
the equations of Multiple-Network Poroelastic Theory (MPET) in the dynamic formulation …

An in silico trial simulates a disease and its corresponding therapies on a cohort of virtual
patients to support the development and evaluation of medical devices, drugs, and …

Computational physiological models are promising tools to enhance the design of clinical
trials and to assist in decision making. Organ-scale haemodynamic models are gaining …

This paper describes the effects of the interaction of cerebral fluids (arterial, capillary and
venous blood, cerebrospinal fluid) on ventricular wall displacement and periventricular …

In this review, we provide a summary of the state-of-the-art in the in silico modelling of
cerebral blood flow (CBF) and its application in in silico clinical trials. CBF plays a key role in …

Graphene and related materials are emerging revolutionary materials due to fascinating
stimuli-responsive physiochemical properties having widespread applications in developing …

Alliance of therapeutic and diagnostic agents under a single umbrella of “theranostics” have
been a boon to the pharmaceutical sector in managing several chronic ailments including …

Throughout the 19th and 20th centuries, aided by advances in medical imaging, discoveries
in physiology and medicine have added nearly 25 years to the average life expectancy. This …