Physiological limitations and opportunities in microbial metabolic engineering

J Montaño López, L Duran, JL Avalos - Nature Reviews Microbiology, 2022 - nature.com
Metabolic engineering can have a pivotal role in increasing the environmental sustainability
of the transportation and chemical manufacturing sectors. The field has already developed …

[HTML][HTML] Technological advancements in valorization of second generation (2G) feedstocks for bio-based succinic acid production

V Narisetty, MC Okibe, K Amulya, EO Jokodola… - Bioresource …, 2022 - Elsevier
Succinic acid (SA) is used as a commodity chemical and as a precursor in chemical industry
to produce other derivatives such as 1, 4-butaneidol, tetrahydrofuran, fumaric acid, and bio …

Biosynthetic pathway and metabolic engineering of succinic acid

X Liu, G Zhao, S Sun, C Fan, X Feng… - … in Bioengineering and …, 2022 - frontiersin.org
Succinic acid, a dicarboxylic acid produced as an intermediate of the tricarboxylic acid (TCA)
cycle, is one of the most important platform chemicals for the production of various high …

Opportunities, challenges, and future perspectives of succinic acid production by Actinobacillus succinogenes

W Dessie, F Xin, W Zhang, Y Jiang, H Wu, J Ma… - Applied microbiology …, 2018 - Springer
Due to environmental issues and the depletion of fossil-based resources, ecofriendly
sustainable biomass-based chemical production has been given more attention recently …

[HTML][HTML] Towards the development of efficient, economic and environmentally friendly downstream processing for bio-based succinic acid

W Dessie, X Luo, GJ Duns, M Wang, Z Qin - Environmental Technology & …, 2023 - Elsevier
Succinic acid (SA) is among the top value-added platform chemicals that can be produced
from renewable resources including organic wastes via microbial fermentation. Extensive …

NMR-based metabolomic investigation on antimicrobial mechanism of Salmonella on cucumber slices treated with organic acids

C Guo, Y He, Y Wang, H Yang - Food Control, 2022 - Elsevier
The potential of organic acids to inactivate foodborne pathogens in food industry has gained
attention, while the sanitizing mechanism of acid stress has not been explained fully at …

Adaptive evolution improves acid tolerance and succinic acid production in Actinobacillus succinogenes

W Zhang, Y Tao, M Wu, F Xin, W Dong, J Zhou, J Gu… - Process …, 2020 - Elsevier
Highlights•An acid-tolerant mutant of A. succinogenes was obtained by adaptive
evolution.•A 20.77 g/L of succinic acid titer with a yield of 0.63 g/g was achieved at pH …

The challenges and prospects of Escherichia coli as an organic acid production host under acid stress

J Yang, J Zhang, Z Zhu, G Du - Applied Microbiology and Biotechnology, 2021 - Springer
Objective Organic acids have a wide range of applications and have attracted the attention
of many industries, and their large-scale applications have led fermentation production to …

Cellular engineering and biocatalysis strategies toward sustainable cadaverine production: state of the art and perspectives

J Mi, S Liu, H Qi, J Huang, X Lan… - … Sustainable Chemistry & …, 2021 - ACS Publications
Cadaverine, a diamine monomer, broadly exists in living organisms participating in
metabolism processes. As a promising substitute of 1, 6-diaminohexane, cadaverine can …

Succinic acid fermentation from agricultural wastes: the producing microorganisms and their engineering strategies

J Wang, A Zeng, W Yuan - Current opinion in environmental science & …, 2022 - Elsevier
Microbial production of succinic acid from renewable feedstock is of great importance for
sustainable development owing to its great economic and technical potential. However, to …