Silk sericin-based materials for biomedical applications

J Liu, L Shi, Y Deng, M Zou, B Cai, Y Song, Z Wang… - Biomaterials, 2022 - Elsevier
Silk sericin, a natural protein extracted from silkworm cocoons, has been extensively studied
and utilized in the biomedical field because of its superior biological activities and …

Silkworm sericin: properties and biomedical applications

RI Kunz, RMC Brancalhão, LFC Ribeiro… - BioMed research …, 2016 - Wiley Online Library
Silk sericin is a natural polymer produced by silkworm, Bombyx mori, which surrounds and
keeps together two fibroin filaments in silk thread used in the cocoon. The recovery and …

Carboxymethyl cellulose/sericin-based hydrogels with intrinsic antibacterial, antioxidant, and anti-inflammatory properties promote re-epithelization of diabetic wounds …

LM El-Samad, MA Hassan, AA Basha… - International Journal of …, 2022 - Elsevier
Diabetic wound healing encounters significant challenges due to the extreme oxidative
stress resulting from excessive inflammation and microbial infections, disrupting the typical …

Silk sericin: A versatile material for tissue engineering and drug delivery

L Lamboni, M Gauthier, G Yang, Q Wang - Biotechnology advances, 2015 - Elsevier
Sericin is an inexpensive glycoprotein obtained as a by-product in the silk industry. Its
variable amino acid composition and diverse functional groups confer upon it attractive …

Silk sericin: A promising sustainable biomaterial for biomedical and pharmaceutical applications

AS Silva, EC Costa, S Reis, C Spencer, RC Calhelha… - Polymers, 2022 - mdpi.com
Silk is a natural composite fiber composed mainly of hydrophobic fibroin and hydrophilic
sericin, produced by the silkworm Bombyx mori. In the textile industry, the cocoons of B. mori …

Designing scaffolds for corneal regeneration

M Ahearne, J Fernández‐Pérez… - Advanced Functional …, 2020 - Wiley Online Library
Corneal blindness is one of the most common causes of vision loss worldwide, affecting
millions of people. To treat these patients, researchers have been examining different …

Processing and characterization of silk sericin from Bombyx mori and its application in biomaterials and biomedicines

TT Cao, YQ Zhang - Materials Science and Engineering: C, 2016 - Elsevier
Bombyx mori silk is composed of 60–80% fibroin, 15–35% sericin and 1–5% non-sericin
component including wax, pigments, sugars and other impurities. For two decades, the …

Pilot production of mesenchymal stem/stromal freeze-dried secretome for cell-free regenerative nanomedicine: a validated GMP-compliant process

E Bari, S Perteghella, D Di Silvestre, M Sorlini… - Cells, 2018 - mdpi.com
In this paper, a pilot production process for mesenchymal stem/stromal freeze-dried
secretome was performed in a validated good manufacturing practice (GMP)-compliant cell …

Silk fibroin nanoparticles for celecoxib and curcumin delivery: ROS-scavenging and anti-inflammatory activities in an in vitro model of osteoarthritis

B Crivelli, E Bari, S Perteghella, L Catenacci… - European Journal of …, 2019 - Elsevier
This paper aims at demonstrating silk fibroin nanoparticles (SFNs) promote anti-
inflammatory properties of celecoxib (CXB) or curcumin (CUR), and could be exploited for …

A comprehensive review of recent advances in silk sericin: Extraction approaches, structure, biochemical characterization, and biomedical applications

M Saad, LM El-Samad, RA Gomaa… - International Journal of …, 2023 - Elsevier
Silks are natural polymers that have been widely used for centuries. Silk consists of a
filament core protein, termed fibroin, and a glue-like coating substance formed of sericin …