Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine encoded within a
functionally polymorphic genetic locus. MIF was initially recognized as a cytokine generated …

The acute respiratory distress syndrome (ARDS) is a common cause of respiratory failure in
critically ill patients and is defined by the acute onset of noncardiogenic pulmonary oedema …

Sepsis and septic shock are among the leading causes of death in intensive care units
worldwide. Numerous studies on their pathophysiology have revealed an imbalance in the …

Wound healing after an injury is essential for life. An in-depth understanding of the healing
process is necessary to ultimately improve the currently limited treatment options for patients …

Lymphocytes were originally thought to form the basis of a 'cancer immunosurveillance'
process that protects immunocompetent hosts against primary tumour development,, but this …

Macrophage migration inhibitory factor (MIF) is a cytokine expressed in various cell types,
including hematopoietic, epithelial, endothelial, mesenchymal and neuronal cells. Altered …

The role of macrophage migration inhibitory factor (MIF) in autoimmunity is underscored by
data showing that common functional polymorphisms in MIF are associated with disease …

Pancreatic cancers with aberrant expression of macrophage migration inhibitory factor (MIF)
are particularly aggressive. To identify key signaling pathways that drive disease …

Sepsis and sepsis-associated multi-organ failure are major challenges for scientists and
clinicians and are a tremendous burden for health-care systems. Despite extensive basic …

For more than a quarter of a century, macrophage migration inhibitory factor (MIF) has been
a mysterious cytokine. In recent years, MIF has assumed an important role as a pivotal …