Mechanisms of action of fluvoxamine for COVID-19: a historical review
Y Hashimoto, T Suzuki, K Hashimoto - Molecular psychiatry, 2022 - nature.com
The ongoing coronavirus disease 2019 (COVID-19) pandemic caused by the novel severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) accelerates the discovery of …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) accelerates the discovery of …
Maternal immune activation by poly I: C as a preclinical model for neurodevelopmental disorders: a focus on autism and schizophrenia
Maternal immune activation (MIA) in response to a viral infection during early and mid-
gestation has been linked through various epidemiological studies to a higher risk for the …
gestation has been linked through various epidemiological studies to a higher risk for the …
[HTML][HTML] Brain changes in a maternal immune activation model of neurodevelopmental brain disorders
L Bergdolt, A Dunaevsky - Progress in neurobiology, 2019 - Elsevier
The developing brain is sensitive to a variety of insults. Epidemiological studies have
identified prenatal exposure to infection as a risk factor for a range of neurological disorders …
identified prenatal exposure to infection as a risk factor for a range of neurological disorders …
Oxidative stress and the pathophysiology and symptom profile of schizophrenia spectrum disorders
Schizophrenia is associated with increased levels of oxidative stress, as reflected by an
increase in the concentrations of damaging reactive species and a reduction in anti-oxidant …
increase in the concentrations of damaging reactive species and a reduction in anti-oxidant …
Arketamine for cognitive impairment in psychiatric disorders
K Hashimoto - European Archives of Psychiatry and Clinical …, 2023 - Springer
Cognitive impairment has been observed in patients with various psychiatric disorders,
including schizophrenia, major depressive disorder (MDD), and bipolar disorder (BD) …
including schizophrenia, major depressive disorder (MDD), and bipolar disorder (BD) …
[HTML][HTML] Essential role of Keap1-Nrf2 signaling in mood disorders: overview and future perspective
K Hashimoto - Frontiers in pharmacology, 2018 - frontiersin.org
Depression is one of the most common mood disorders with a high rate of relapse.
Accumulating evidence suggests that the transcription factor Kelch-like erythroid cell-derived …
Accumulating evidence suggests that the transcription factor Kelch-like erythroid cell-derived …
The potential use of l-sulforaphane for the treatment of chronic inflammatory diseases: A review of the clinical evidence
N Mazarakis, K Snibson, PV Licciardi, TC Karagiannis - Clinical nutrition, 2020 - Elsevier
Summary According to the World Health Organisation, 70% of all deaths globally can be
attributed to chronic inflammatory diseases such as rheumatoid arthritis, inflammatory bowel …
attributed to chronic inflammatory diseases such as rheumatoid arthritis, inflammatory bowel …
[HTML][HTML] Early identification and intervention of schizophrenia: insight from hypotheses of glutamate dysfunction and oxidative stress
Schizophrenia is a severe mental disorder which leads to functional deterioration. Early
detection and intervention are vital for better prognosis. However, the diagnosis of …
detection and intervention are vital for better prognosis. However, the diagnosis of …
[HTML][HTML] Translational opportunities in the prenatal immune environment: Promises and limitations of the maternal immune activation model
MD Bauman, J Van de Water - Neurobiology of disease, 2020 - Elsevier
The prenatal environment, and in particular, the maternal-fetal immune environment, has
emerged as a targeted area of research for central nervous system (CNS) diseases with …
emerged as a targeted area of research for central nervous system (CNS) diseases with …
[HTML][HTML] Long-lasting beneficial effects of maternal intake of sulforaphane glucosinolate on gut microbiota in adult offspring
Mounting evidence suggests the impact of maternal diet on the health of offspring. We
reported that maternal diet of sulforaphane glucosinolate (SGS) could prevent behavioral …
reported that maternal diet of sulforaphane glucosinolate (SGS) could prevent behavioral …