The ego in psychedelic drug action–ego defenses, ego boundaries, and the therapeutic role of regression
T Buchborn, HS Kettner, L Kärtner… - Frontiers in …, 2023 - frontiersin.org
The ego is one of the most central psychological constructs in psychedelic research and a
key factor in psychotherapy, including psychedelic-assisted forms of psychotherapy. Despite …
key factor in psychotherapy, including psychedelic-assisted forms of psychotherapy. Despite …
Hallucinogenic potential: a review of psychoplastogens for the treatment of opioid use disorder
MG Hornick, A Stefanski - Frontiers in Pharmacology, 2023 - frontiersin.org
The United States is entering its fourth decade of the opioid epidemic with no clear end in
sight. At the center of the epidemic is an increase in opioid use disorder (OUD), a complex …
sight. At the center of the epidemic is an increase in opioid use disorder (OUD), a complex …
The ReCoDe addiction research consortium: Losing and regaining control over drug intake—Findings and future perspectives
Substance use disorders (SUDs) are seen as a continuum ranging from goal‐directed and
hedonic drug use to loss of control over drug intake with aversive consequences for mental …
hedonic drug use to loss of control over drug intake with aversive consequences for mental …
Methyl transfer in psilocybin biosynthesis
J Hudspeth, K Rogge, S Dörner, M Müll… - Nature …, 2024 - nature.com
Psilocybin, the natural hallucinogen produced by Psilocybe (“magic”) mushrooms, holds
great promise for the treatment of depression and several other mental health conditions …
great promise for the treatment of depression and several other mental health conditions …
μ-opioid receptor agonists and psychedelics: pharmacological opportunities and challenges
LM Salinsky, CR Merritt, JC Zamora… - Frontiers in …, 2023 - frontiersin.org
Opioid misuse and opioid-involved overdose deaths are a massive public health problem
involving the intertwined misuse of prescription opioids for pain management with the …
involving the intertwined misuse of prescription opioids for pain management with the …
Current Perspectives on the Clinical Research and Medicalization of Psychedelic Drugs for Addiction Treatments: Safety, Efficacy, Limitations and Challenges
A Gomez-Escolar, D Folch-Sanchez, J Stefaniuk… - CNS Drugs, 2024 - Springer
Mental health disorders and substance use disorders (SUDs) in particular, contribute greatly
to the global burden of disease. Psychedelics, including entactogens and dissociative …
to the global burden of disease. Psychedelics, including entactogens and dissociative …
Established sensitization of ethanol-induced locomotor activity is not reversed by psilocybin or the 5-HT2A receptor agonist TCB-2 in male DBA/2J mice
PJ Fletcher, Z Li, XD Ji, AD Lê - Pharmacology Biochemistry and Behavior, 2024 - Elsevier
Rationale Psychedelic drugs, which share in common 5-HT 2A receptor agonist activity,
have shown promise in treating alcohol-use disorders (AUDs). Repeated exposure to …
have shown promise in treating alcohol-use disorders (AUDs). Repeated exposure to …
Psilocybin-assisted therapy for severe alcohol use disorder: protocol for a double-blind, randomized, placebo-controlled, 7-month parallel-group phase II superiority …
L Vanderijst, F Hever, A Buot, C Dauré, J Benoit… - BMC psychiatry, 2024 - Springer
Background A significant number of individuals with alcohol use disorder remain
unresponsive to currently available treatments, which calls for the development of new …
unresponsive to currently available treatments, which calls for the development of new …
Neuro-circuitry of Impulsivity and its Relation to Substance Use Disorders
P Giovannelli, H Pfister - Archives of Clinical Psychiatry, 2023 - archivespsy.com
Within the fields of neuroscience and psychology, comprehending the complex interactions
between impulsivity and substance use disorders (SUDs) is an important goal. Decision …
between impulsivity and substance use disorders (SUDs) is an important goal. Decision …