Abstract Cyclooxygenase-2 (COX-2), an inducible form of the enzyme that catalyzes the first
step in the synthesis of prostanoids, is associated with inflammatory diseases and …

G protein‐coupled receptors (GPCRs) and heterotrimeric G proteins play central roles in a
diverse array of cellular processes. As such, dysregulation of GPCRs and their coupled …

Gallic acid, a predominant polyphenol, has been shown to inhibit carcinogenesis in animal
models and in vitro cancerous cell lines. The inhibitory effect of gallic acid on cancer cell …

A wide array of phenolic substances, particularly those present in edible and medicinal
plants, have been reported to possess substantial anticarcinogenic and antimutagenic …

G-protein-coupled receptors (GPCRs), the largest family of cell-surface molecules involved
in signal transmission, have recently emerged as crucial players in tumour growth and …

Group 2 innate lymphoid cells (ILC2s) are involved in human diseases, such as allergy,
atopic dermatitis and nasal polyposis, but their function in human cancer remains unclear …

Several recent studies have identified nuclear factor-κB as a key modulator in driving
inflammation to cancers. Besides this transcription factor, essential in regulating …

BACKGROUND The cyclooxygenase (COX) enzyme catalyzes the formation of
prostaglandins, which can affect cell proliferation and alter the response of the immune …

Linoleic and alpha-linolenic acids, obtained from plant material in the diet are the precursors
in tissues of two families with opposing effects which are referred to as “essential fatty …

BACKGROUND Because a role for nuclear factor‐κB (NF‐κB) has been implicated in the
pathogenesis of pancreatic carcinoma, this transcription factor is a potential target for the …