Phage puppet masters of the marine microbial realm

M Breitbart, C Bonnain, K Malki, NA Sawaya - Nature microbiology, 2018 - nature.com
Viruses numerically dominate our oceans; however, we have only just begun to document
the diversity, host range and infection dynamics of marine viruses, as well as the subsequent …

Resistance development to bacteriophages occurring during bacteriophage therapy

F Oechslin - Viruses, 2018 - mdpi.com
Bacteriophage (phage) therapy, ie, the use of viruses that infect bacteria as antimicrobial
agents, is a promising alternative to conventional antibiotics. Indeed, resistance to antibiotics …

Marine DNA viral macro-and microdiversity from pole to pole

AC Gregory, AA Zayed, N Conceição-Neto… - Cell, 2019 - cell.com
Microbes drive most ecosystems and are modulated by viruses that impact their lifespan,
gene flow, and metabolic outputs. However, ecosystem-level impacts of viral community …

Molecular and evolutionary determinants of bacteriophage host range

PA de Jonge, FL Nobrega, SJJ Brouns, BE Dutilh - Trends in microbiology, 2019 - cell.com
The host range of a bacteriophage is the taxonomic diversity of hosts it can successfully
infect. Host range, one of the central traits to understand in phages, is determined by a range …

Microbiomes in light of traits: a phylogenetic perspective

JBH Martiny, SE Jones, JT Lennon, AC Martiny - Science, 2015 - science.org
BACKGROUND Microbial communities—microbiomes—are intricately linked to human
health and critical ecosystem services. New technologies allow the rapid characterization of …

Marine microbial community dynamics and their ecological interpretation

JA Fuhrman, JA Cram, DM Needham - Nature Reviews Microbiology, 2015 - nature.com
Recent advances in studying the dynamics of marine microbial communities have shown
that the composition of these communities follows predictable patterns and involves complex …

Bacteria–phage coevolution as a driver of ecological and evolutionary processes in microbial communities

B Koskella, MA Brockhurst - FEMS microbiology reviews, 2014 - academic.oup.com
Bacteria–phage coevolution, the reciprocal evolution between bacterial hosts and the
phages that infect them, is an important driver of ecological and evolutionary processes in …

Viral dark matter and virus–host interactions resolved from publicly available microbial genomes

S Roux, SJ Hallam, T Woyke, MB Sullivan - elife, 2015 - elifesciences.org
The ecological importance of viruses is now widely recognized, yet our limited knowledge of
viral sequence space and virus–host interactions precludes accurate prediction of their roles …

Multistep diversification in spatiotemporal bacterial-phage coevolution

E Shaer Tamar, R Kishony - Nature Communications, 2022 - nature.com
The evolutionary arms race between phages and bacteria, where bacteria evolve resistance
to phages and phages retaliate with resistance-countering mutations, is a major driving force …

Rising to the challenge: accelerated pace of discovery transforms marine virology

JR Brum, MB Sullivan - Nature Reviews Microbiology, 2015 - nature.com
Marine viruses have important roles in microbial mortality, gene transfer, metabolic
reprogramming and biogeochemical cycling. In this Review, we discuss recent technological …