N-Heterocyclic carbenes, despite being isolated and characterized three decades ago, still
capture scientists' interest as versatile, modular and strongly coordinating moieties. In the …

Atropisomeric molecules have found proven applications and have shown promising
potential in chemistry and medicine. The design of N‐heterocyclic carbene (NHC) catalyzed …

Radical/radical cross-coupling reactions represent an efficient and straightforward approach
for the construction of chemical bonds and accordingly have drawn increasing attention over …

Conspectus In nature, enzymes are a powerful medium for the construction of
enantiomerically pure chemicals, which always inspires synthetic chemists to explore new …

Axial chirality widely exists in natural products, pharmaceutical compounds, and other
functional molecules; these axially chiral compounds also find wide utility as catalysts or …

In nature, a number of enzymes use thiamine diphosphate as a coenzyme to catalyze the
pyruvate decarboxylation. The resultant enamine, a so-called “Breslow intermediate,” is …

Three-component carboacylation of simple alkenes with readily available reagents is
challenging. Transition metal-catalysed intermolecular carboacylation works for alkenes with …

Despite the great potential of radical chemistry in organic synthesis, N‐heterocyclic carbene
(NHC)‐catalyzed reactions involving radical intermediates are not well explored. This …

N-Heterocyclic carbene (NHC) catalysis has emerged as a versatile tool in modern synthetic
chemistry. Further increasing the complexity, several processes have been introduced that …

Conspectus This Account is aimed at highlighting the recent developments in the N-
heterocyclic carbene (NHC)-catalyzed generation of α, β-unsaturated acylazolium …