More than 250 million people are living with chronic hepatitis B despite the availability of
highly effective vaccines and oral antivirals. Although innate and adaptive immune cells play …

Acute-on-chronic liver failure (ACLF) is a multifaceted condition with poor treatment options
and high short-term mortality. ACLF can develop in patients with or without liver cirrhosis …

Liver fibrosis is the common pathological basis of all chronic liver diseases, and is the
necessary stage for the progression of chronic liver disease to cirrhosis. As one of …

Background. T‐helper 17 (Th17) and CD4+ CD25+ T‐regulatory (Treg) cells play important
roles in the pathogenesis of hepatitis B virus‐related acute‐on‐chronic liver failure (HBV …

Introduction Changes in the expression of cyto-and chemokines due to alcohol-associated
liver disease (ALD) have been reported to be both protective and pathogenic. This study …

Acute-on-chronic liver failure (ACLF) is a severe life-threatening condition with high risk of
multiorgan failure, sepsis, and mortality. ACLF activates a multifaceted interplay of both …

Background Systemic inflammation is associated with the development and progression of
hepatitis B-associated acute-on-chronic liver failure (HBV-ACLF). The neutrophil-to …

Abstract Background and Aims Little is known about the mechanisms of IL‐17 secreting T
cells accumulation in HBV‐transfected livers. Here, we investigated the role of the …

Background: Liver cirrhosis contributes to high liver-related mortality globally. Systemic
inflammation mediated by immune cells contributes to the progression of liver cirrhosis …

Hepatitis B virus‐related acute‐on‐chronic liver failure (HBV‐ACLF) is relatively common in
China and has complex pathogenesis, difficult clinical treatment, and poor prognosis …