Highlights•The methanogens consist of the hydrogenotrophs and the methylotrophs.•The
methanogens are metabolically more versatile than previously appreciated.•Alternative …

Biclustering is a powerful data mining technique that allows clustering of rows and columns,
simultaneously, in a matrix-format data set. It was first applied to gene expression data in …

Current understanding of heat shock response has been complicated by the fact that heat
stress is inevitably accompanied by changes in specific growth rates and growth stages. In …

Background Algae accumulate lipids to endure different kinds of environmental stresses
including macronutrient starvation. Although this response has been extensively studied, an …

Microbial growth curves are used to study differential effects of media, genetics, and stress
on microbial population growth. Consequently, many modeling frameworks exist to capture …

Transcription termination defines accurate transcript 3′-ends and ensures programmed
transcriptomes, making it critical to life. However, transcription termination mechanisms …

Hydrogenotrophic methanogenesis occurs in multiple environments, ranging from the
intestinal tracts of animals to anaerobic sediments and hot springs. Energy conservation in …

The rapid autotrophic growth of the methanogenic archaeon Methanococcus maripaludis on
H2 and CO2 makes it an attractive microbial chassis to inexpensively produce biochemicals …

Biological methanogenesis evolved early in Earth's history and was likely already a major
process by 3.5 Ga. Modern methanogenesis is now a key process in virtually all anaerobic …

The cMonkey integrated biclustering algorithm identifies conditionally co-regulated modules
of genes (biclusters). cMonkey integrates various orthogonal pieces of information which …