Pectic polysaccharides: Targeting gut microbiota in obesity and intestinal health

HB Lee, YS Kim, HY Park - Carbohydrate polymers, 2022 - Elsevier
The gut microbiome is a complex ecosystem of the host body that maintains a balance with
its host. In this context, dysbiosis can lead to inflammatory response, immune dysregulation …

Impact of lifestyles (diet and exercise) on vascular health: oxidative stress and endothelial function

AWC Man, H Li, N Xia - Oxidative medicine and cellular …, 2020 - Wiley Online Library
Healthy lifestyle and diet are associated with significant reduction in risk of obesity, type 2
diabetes, and cardiovascular diseases. Oxidative stress and the imbalance between …

An insight into brown/beige adipose tissue whitening, a metabolic complication of obesity with the multifactorial origin

K Ziqubu, PV Dludla, SXH Mthembu… - Frontiers in …, 2023 - frontiersin.org
Brown adipose tissue (BAT), a thermoregulatory organ known to promote energy
expenditure, has been extensively studied as a potential avenue to combat obesity …

Curcumin reduces adipose tissue inflammation and alters gut microbiota in diet‐induced obese male mice

T Islam, I Koboziev, K Albracht‐Schulte… - Molecular nutrition & …, 2021 - Wiley Online Library
Scope Obesity prevalence continues to increase and contribute to metabolic diseases,
potentially by driving systemic inflammation. Curcumin is an anti‐inflammatory spice with …

[HTML][HTML] Saturated fatty acids dampen the immunogenicity of cancer by suppressing STING

BR Heath, W Gong, HF Taner, L Broses, K Okuyama… - Cell reports, 2023 - cell.com
Oncogenes destabilize STING in epithelial cell-derived cancer cells, such as head and neck
squamous cell carcinomas (HNSCCs), to promote immune escape. Despite the abundance …

High fat diet and its effects on cognitive health: alterations of neuronal and vascular components of brain

S Sharma - Physiology & Behavior, 2021 - Elsevier
It has been well recognized that intake of diets rich in saturated fats could result in
development of metabolic disorders such as type 2 diabetes mellitus, obesity and …

[HTML][HTML] Gellan gum prevents non-alcoholic fatty liver disease by modulating the gut microbiota and metabolites

MH Do, HHL Lee, JE Lee, M Park, MJ Oh, HB Lee… - Food Chemistry, 2023 - Elsevier
Gellan gum (GG) is an anionic polysaccharide used as an additive in the food industry.
However, the effect of GG on gut microbiota regulation and nonalcoholic fatty liver disease …

Sex-specific effects of a high fat diet on aortic inflammation and dysfunction

V Tran, H Brettle, H Diep, QN Dinh, M O'Keeffe… - Scientific Reports, 2023 - nature.com
Obesity and vascular dysfunction are independent and sexually dimorphic risk factors for
cardiovascular disease. A high fat diet (HFD) is often used to model obesity in mice, but the …

The Geometric Framework for Nutrition and Its Application to Rodent Models

AM Senior, D Raubenheimer… - Annual Review of …, 2025 - annualreviews.org
Rodents have been the primary model for mammalian nutritional physiology for decades.
Despite an extensive body of literature, controversies remain around the effects of specific …

[HTML][HTML] Sucrose overconsumption impairs AgRP neuron dynamics and promotes palatable food intake

CM Lorch, NW Hayes, JL Xia, SW Fleps, HE McMorrow… - Cell reports, 2024 - cell.com
Rapid gut-brain communication is critical to maintain energy balance and is disrupted in diet-
induced obesity. In particular, the role of carbohydrate overconsumption in the regulation of …