Limitations of current therapeutic options, possible drug targets and scope of natural products in control of leishmaniasis

N Tiwari, MR Gedda, VK Tiwari… - Mini Reviews in …, 2018 - ingentaconnect.com
Soon after the identification of Leishmania parasite as a causative agent, the pentavalent
antimony compounds have been the mainstay to treat all forms of leishmaniasis. Due to …

Emerging therapeutic targets for treatment of leishmaniasis

S Sundar, B Singh - Expert opinion on therapeutic targets, 2018 - Taylor & Francis
Introduction: Parasitic diseases that pose a threat to human life include leishmaniasis–
caused by protozoan parasite Leishmania species. Existing drugs have limitations due to …

Experimental evidence of harmful effects of Crithidia mellificae and Lotmaria passim on honey bees

T Gómez-Moracho, M Buendía-Abad, M Benito… - International Journal for …, 2020 - Elsevier
The trypanosomatids Crithidia mellificae and Lotmaria passim are very prevalent in honey
bee colonies and potentially contribute to colony losses that currently represent a serious …

Health from Brazilian Amazon food wastes: Bioactive compounds, antioxidants, antimicrobials, and potentials against cancer and oral diseases

RS Lima, APA de Carvalho… - Critical Reviews in Food …, 2023 - Taylor & Francis
Brazilian Amazon contains over 30,000 plant species and foods rich in bioactive compounds
such as terpenes, phenolic acids, alkaloids, and flavonoids, of potential health benefits …

An overview of the chemical constituents from the genus Delphinium reported in the last four decades

T Yin, L Cai, Z Ding - RSC advances, 2020 - pubs.rsc.org
Species of the genus Delphinium have been extensively used for different purposes by
various civilizations worldwide since antiquity. Phytochemical investigations on Delphinium …

Natural acylated flavonoids: their chemistry and biological merits in context to molecular docking studies

AF Essa, M Teleb, DM El-Kersh, AENG El Gendy… - Phytochemistry …, 2023 - Springer
Acylated flavonoids are widely distributed natural dietary bioactives with several health
attributes. A large diversity of acylated flavonoids with interesting biological potentialities …

Mining chemodiversity from biodiversity: pharmacophylogeny of medicinal plants of Ranunculaceae

HAO Da-Cheng, X Pei-Gen, MA Hong-Ying… - Chinese journal of …, 2015 - Elsevier
This paper reports a pharmacophylogenetic study of a medicinal plant family,
Ranunculaceae, investigating the correlations between their phylogeny, chemical …

A review of cytotoxic plants of the Indian subcontinent and a broad-spectrum analysis of their bioactive compounds

K Mazumder, B Biswas, IM Raja, K Fukase - Molecules, 2020 - mdpi.com
Cancer or uncontrolled cell proliferation is a major health issue worldwide and is the second
leading cause of deaths globally. The high mortality rate and toxicity associated with cancer …

Review on natural products as an alternative to contemporary anti-leishmanial therapeutics

S Raj, S Sasidharan, SN Balaji, VK Dubey… - Journal of Proteins and …, 2020 - Springer
Leishmaniasis is a vector-borne protozoan disease caused by an intracellular parasite
which globally affects 350 million people. This infectious disease mainly affects …

[HTML][HTML] Antileishmanial activity of essential oil and 6, 7-dehydroroyleanone isolated from Tetradenia riparia

IG Demarchi, MV Thomazella… - Experimental …, 2015 - Elsevier
Tetradenia riparia plant is used as a traditional medicine in Africa for the treatment of
inflammatory and infectious diseases as like parasitic. Therapy for leishmaniasis caused by …