Magnesium as an enzymatic activator is essential for various physiological functions such as
cell cycle, metabolic regulation, muscle contraction, and vasomotor tone. A growing body of …

Magnesium is an essential element of life, involved in the regulation of metabolism and
homeostasis of all the tissues. It also regulates immunological functions, acting on the cells …

Different studies have confirmed that P2X purinergic receptors play a key role in
inflammation. Activation of P2X purinergic receptors can release inflammatory cytokines and …

Chronic ulceration of the colon is associated with the activation of TLR4/NF-κB and
P2X7R/NLRP3 signaling pathways. We investigated the effect of individual or combined …

Preterm birth (PTB) is defined as delivery before 37 weeks of gestation. Globally, 15 million
infants are born prematurely, putting these children at an increased risk of mortality and …

Despite the development of a number of vaccines for COVID-19, there remains a need for
prevention and treatment of the virus SARS-CoV-2 and the ensuing disease COVID-19. This …

Neuropathic Pain (NPP) is caused by direct or indirect damage to the nervous system and is
a common symptom of many diseases. Clinically, drugs are usually used to suppress pain …

Magnesium is the fourth most common mineral in the human body and the second richest
intracellular cation. This element is necessary for many physiological reactions, especially in …

Diabetic cardiomyopathy (DCM) is a critical complication of long-term chronic diabetes
mellitus, and it is characterized by myocardial fibrosis and myocardial hypertrophy. Previous …

Crohn's disease is a chronic inflammatory bowel disease and the NLRP3 inflammasome
plays an important role in Crohn's disease. Previous studies have shown that Herb …