miRNAs as biomarkers in disease: latest findings regarding their role in diagnosis and prognosis
CE Condrat, DC Thompson, MG Barbu, OL Bugnar… - Cells, 2020 - mdpi.com
MicroRNAs (miRNAs) represent a class of small, non-coding RNAs with the main roles of
regulating mRNA through its degradation and adjusting protein levels. In recent years …
regulating mRNA through its degradation and adjusting protein levels. In recent years …
[HTML][HTML] The β-secretase BACE1 in Alzheimer's disease
BACE1 (beta-site amyloid precursor protein cleaving enzyme 1) was initially cloned and
characterized in 1999. It is required for the generation of all monomeric forms of amyloid-β …
characterized in 1999. It is required for the generation of all monomeric forms of amyloid-β …
Neuroprotective effects of coffee bioactive compounds: a review
K Socała, A Szopa, A Serefko, E Poleszak… - International journal of …, 2020 - mdpi.com
Coffee is one of the most widely consumed beverages worldwide. It is usually identified as a
stimulant because of a high content of caffeine. However, caffeine is not the only coffee …
stimulant because of a high content of caffeine. However, caffeine is not the only coffee …
Role of gut microbiota and nutrients in amyloid formation and pathogenesis of Alzheimer disease
F Pistollato, S Sumalla Cano, I Elio… - Nutrition …, 2016 - academic.oup.com
It has been hypothesized that alterations in the composition of the gut microbiota might be
associated with the onset of certain human pathologies, such as Alzheimer disease, a …
associated with the onset of certain human pathologies, such as Alzheimer disease, a …
[HTML][HTML] Circulating microRNAs as potential biomarkers for psychiatric and neurodegenerative disorders
MMJ Van den Berg, J Krauskopf, JG Ramaekers… - Progress in …, 2020 - Elsevier
Circulating microRNAs (cimiRNAs) are a class of non-encoding RNAs found in bodily fluids
such as blood, cerebrospinal fluid (CSF) and tears. CimiRNAs have been implicated as …
such as blood, cerebrospinal fluid (CSF) and tears. CimiRNAs have been implicated as …
MiR-155: an important regulator of neuroinflammation
VD Zingale, A Gugliandolo, E Mazzon - International Journal of Molecular …, 2021 - mdpi.com
MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression
at the post-transcriptional level and that play an important role in many cellular processes …
at the post-transcriptional level and that play an important role in many cellular processes …
Omics sciences for systems biology in Alzheimer's disease: State-of-the-art of the evidence
Alzheimer's disease (AD) is characterized by non-linear, genetic-driven pathophysiological
dynamics with high heterogeneity in biological alterations and disease spatial-temporal …
dynamics with high heterogeneity in biological alterations and disease spatial-temporal …
Epigenetics of Alzheimer's disease
There are currently no validated biomarkers which can be used to accurately diagnose
Alzheimer's disease (AD) or to distinguish it from other dementia-causing neuropathologies …
Alzheimer's disease (AD) or to distinguish it from other dementia-causing neuropathologies …
Deficiency in the ubiquitin conjugating enzyme UBE2A in Alzheimer's disease (AD) is linked to deficits in a natural circular miRNA-7 sponge (circRNA; ciRS-7)
Y Zhao, PN Alexandrov, V Jaber, WJ Lukiw - Genes, 2016 - mdpi.com
Our understanding of the highly specialized functions for small non-coding single-stranded
RNA (ssRNA) in the transcriptome of the human central nervous system (CNS) continues to …
RNA (ssRNA) in the transcriptome of the human central nervous system (CNS) continues to …
[HTML][HTML] Are circulating microRNAs peripheral biomarkers for Alzheimer's disease?
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by
memory loss, multiple cognitive abnormalities and intellectual impairments. Currently, there …
memory loss, multiple cognitive abnormalities and intellectual impairments. Currently, there …