Lysosomes and lysosomal cathepsins in cell death
Lysosomes are the key degradative compartments of the cell. Lysosomal cathepsins, which
are enclosed in the lysosomes, help to maintain the homeostasis of the cell's metabolism by …
are enclosed in the lysosomes, help to maintain the homeostasis of the cell's metabolism by …
Heparan sulfate and heparan sulfate proteoglycans in cancer initiation and progression
A Nagarajan, P Malvi, N Wajapeyee - Frontiers in endocrinology, 2018 - frontiersin.org
Heparan sulfate (HS) are complex unbranched carbohydrate chains that are heavily
modified by sulfate and exist either conjugated to proteins or as free, unconjugated chains …
modified by sulfate and exist either conjugated to proteins or as free, unconjugated chains …
Lysosomal–mitochondrial cross-talk during cell death
U Repnik, B Turk - Mitochondrion, 2010 - Elsevier
Lysosomes are membrane-bound organelles, which contain an arsenal of different
hydrolases, enabling them to act as the terminal degradative compartment of the …
hydrolases, enabling them to act as the terminal degradative compartment of the …
The endolysosomal system in cell death and survival
U Repnik, MH Česen, B Turk - Cold Spring Harbor …, 2013 - cshperspectives.cshlp.org
The endocytic pathway is a system specialized for the uptake of compounds from the cell
microenvironment for their degradation. It contains an arsenal of hydrolases, including …
microenvironment for their degradation. It contains an arsenal of hydrolases, including …
RGTA® or ReGeneraTing Agents mimic heparan sulfate in regenerative medicine: from concept to curing patients
D Barritault, M Gilbert-Sirieix, KL Rice, F Siñeriz… - Glycoconjugate …, 2017 - Springer
The importance of extracellular matrix (ECM) integrity in maintaining normal tissue function
is highlighted by numerous pathologies and situations of acute and chronic injury …
is highlighted by numerous pathologies and situations of acute and chronic injury …
Repair effects of astragalus polysaccharides with different molecular weights on oxidatively damaged HK-2 cells
J Han, D Guo, XY Sun, JM Wang, JM Ouyang… - Scientific Reports, 2019 - nature.com
This study investigated the repair effects of three Astragalus polysaccharides (APSs) with
different molecular weights (Mws) on injured human renal proximal tubular epithelial (HK-2) …
different molecular weights (Mws) on injured human renal proximal tubular epithelial (HK-2) …
New roles of glycosaminoglycans in α-synuclein aggregation in a cellular model of Parkinson disease
S Lehri-Boufala, MO Ouidja, V Barbier-Chassefière… - PloS one, 2015 - journals.plos.org
The causes of Parkinson disease (PD) remain mysterious, although some evidence
supports mitochondrial dysfunctions and α-synuclein accumulation in Lewy bodies as major …
supports mitochondrial dysfunctions and α-synuclein accumulation in Lewy bodies as major …
Mitochondrial proteomic analysis of cisplatin resistance in ovarian cancer
NP Chappell, P Teng, BL Hood, G Wang… - Journal of proteome …, 2012 - ACS Publications
Epithelial ovarian cancer (EOC) is the leading cause of death among women with
gynecologic malignancies and accounts for approximately 6% of cancer deaths among …
gynecologic malignancies and accounts for approximately 6% of cancer deaths among …
In vitro anti-inflammatory effects of hyaluronic acid in ethanol-induced damage in skin cells
MG Neuman, RM Nanau… - Journal of pharmacy …, 2011 - journals.library.ualberta.ca
Ethyl alcohol (ethanol) is commonly applied in cosmetic and pharmaceutical preparations,
as well as disinfectant for chronic wounds. Objective: The present study aimed to appraise …
as well as disinfectant for chronic wounds. Objective: The present study aimed to appraise …
Glycosaminoglycan and proteoglycan biotherapeutics in articular cartilage protection and repair strategies: novel approaches to visco‐supplementation in …
The aim of this study is to review developments in glycosaminoglycan and proteoglycan
research relevant to cartilage repair biology and in particular the treatment of osteoarthritis …
research relevant to cartilage repair biology and in particular the treatment of osteoarthritis …