STING (STimulator of INterferon Genes) has recently been identified as being essential for
controlling host defense countermeasures triggered by microbial cytosolic DNA and …

Pioneering electron microscopy studies defined two primary populations of ribosomes in
eukaryotic cells: one freely dispersed through the cytoplasm and the other bound to the …

Multipass membrane proteins play numerous roles in biology and include receptors,
transporters, ion channels and enzymes,. How multipass proteins are co-translationally …

The innate immune system is critical for the early detection of invading pathogens and for
initiating cellular host defence countermeasures, which include the production of type I …

The cellular innate immune system is essential for recognizing pathogen infection and for
establishing effective host defence. But critical molecular determinants responsible for …

The “Gold Standard” in Biochemistry text books. Biochemistry 4e, is a modern classic that
has been thoroughly revised. Don and Judy Voet explain biochemical concepts while …

Cotranslational protein translocation is a universally conserved process for secretory and
membrane protein biosynthesis. Nascent polypeptides emerging from a translating …

The endoplasmic reticulum (ER) consists of the nuclear envelope and a peripheral network
of tubules and membrane sheets. The tubules are shaped by the curvature-stabilizing …

The evolution of mass spectrometry–based proteomic technologies has advanced our
understanding of the complex and dynamic nature of proteomes while concurrently …

The Sec61 or SecY channel, a universally conserved protein-conducting channel,
translocates proteins across and integrates proteins into the eukaryotic endoplasmic …