Merkel cell carcinoma
Merkel cell carcinoma (MCC) is a rare but highly aggressive skin cancer with
neuroendocrine features. MCC pathogenesis is associated with either the presence of …
neuroendocrine features. MCC pathogenesis is associated with either the presence of …
[HTML][HTML] Merkel cell carcinoma: epidemiology, prognosis, therapy and unmet medical needs
D Schadendorf, C Lebbé, A Zur Hausen… - European journal of …, 2017 - Elsevier
Merkel cell carcinoma (MCC) is a rare skin cancer that is associated with Merkel cell
polyomavirus infection in most cases. Incidence rates of MCC have increased in past …
polyomavirus infection in most cases. Incidence rates of MCC have increased in past …
The biology and treatment of Merkel cell carcinoma: current understanding and research priorities
PW Harms, KL Harms, PS Moore… - Nature reviews Clinical …, 2018 - nature.com
Merkel cell carcinoma (MCC) is a rare and aggressive skin cancer associated with
advanced age and immunosuppression. Over the past decade, an association has been …
advanced age and immunosuppression. Over the past decade, an association has been …
Molecular mechanisms of viral oncogenesis in humans
NA Krump, J You - Nature Reviews Microbiology, 2018 - nature.com
Viral infection is a major contributor to the global cancer burden. Recent advances have
revealed that seven known oncogenic viruses promote tumorigenesis through shared host …
revealed that seven known oncogenic viruses promote tumorigenesis through shared host …
Mutational landscape of MCPyV-positive and MCPyV-negative Merkel cell carcinomas with implications for immunotherapy
Merkel cell carcinoma (MCC) is a rare but highly aggressive cutaneous neuroendocrine
carcinoma, associated with the Merkel cell polyomavirus (MCPyV) in 80% of cases. To …
carcinoma, associated with the Merkel cell polyomavirus (MCPyV) in 80% of cases. To …
Viral infections
JC Sterling - Rook's Textbook of Dermatology, Ninth Edition, 2016 - Wiley Online Library
Skin disease due to viruses may be a primary infection of the epidermis or may arise
secondary to systemic infection. Depending on the virus, the effects may be necrotic damage …
secondary to systemic infection. Depending on the virus, the effects may be necrotic damage …
Why do viruses cause cancer? Highlights of the first century of human tumour virology
The year 2011 marks the centenary of Francis Peyton Rous's landmark experiments on an
avian cancer virus. Since then, seven human viruses have been found to cause 10–15% of …
avian cancer virus. Since then, seven human viruses have been found to cause 10–15% of …
Merkel cell polyomavirus and two previously unknown polyomaviruses are chronically shed from human skin
RM Schowalter, DV Pastrana, KA Pumphrey… - Cell host & …, 2010 - cell.com
Mounting evidence indicates that Merkel cell polyomavirus (MCV), a circular double-
stranded DNA virus, is a causal factor underlying a highly lethal form of skin cancer known …
stranded DNA virus, is a causal factor underlying a highly lethal form of skin cancer known …
Human skin microbiota: high diversity of DNA viruses identified on the human skin by high throughput sequencing
V Foulongne, V Sauvage, C Hebert, O Dereure… - PloS one, 2012 - journals.plos.org
The human skin is a complex ecosystem that hosts a heterogeneous flora. Until recently, the
diversity of the cutaneous microbiota was mainly investigated for bacteria through culture …
diversity of the cutaneous microbiota was mainly investigated for bacteria through culture …
Seroepidemiology of human polyomaviruses
In addition to the previously characterized viruses BK and JC, three new human
polyomaviruses (Pys) have been recently identified: KIV, WUV, and Merkel Cell Py (MCV) …
polyomaviruses (Pys) have been recently identified: KIV, WUV, and Merkel Cell Py (MCV) …