Parasitic diseases affect billions of people and are considered a major public health issue.
Close to 400 species are estimated to parasitize humans, of which around 90 are …

Helminths facilitate their parasitic existence through the production and secretion of different
molecules, including proteins. Some helminth proteins can manipulate the host's immune …

With the aim of characterizing the molecules involved in the interaction of Dicrocoelium
dendriticum adults and the host, we have performed proteomic analyses of the external …

Hookworms infect more than 700 million people worldwide and cause more morbidity than
most other human parasitic infections. Nippostrongylus brasiliensis (the rat hookworm) has …

Recent studies have shown the importance of exosomes in the host-parasite relationship.
These vesicles are an important part of the excretory/secretory pathway for proteins with the …

Serine protease inhibitors (serpins) regulate proteolytic events within diverse biological
processes, including digestion, coagulation, inflammation and immune responses. The …

Abstract The Excretory/Secretory (ES) proteins of parasites are involved in invasion and
colonization of their hosts. In addition, since ES proteins circulate in the extracellular space …

Background Helminth infections are among the most prevalent neglected tropical diseases,
causing an enormous impact in global health and the socioeconomic growth of developing …

Trematode infections are among the most neglected tropical diseases despite their
worldwide distribution and extraordinary ability to parasitise many different host species and …

Intestinal trematodes constitute a major group of helminths that parasitize humans and
animals with relevant morbidity and mortality. Despite the importance of the intestinal …