Cholesterol is an important component for cell physiology. It regulates the fluidity of cell
membranes and determines the physical and biochemical properties of proteins. In the …

Cannabis sativa has been associated with contradictory effects upon seizure states despite
its medicinal use by numerous people with epilepsy. We have recently shown that the …

Millions of people worldwide receive agents targeting the renin–angiotensin system (RAS)
to treat hypertension or statins to lower cholesterol. The RAS and cholesterol metabolic …

Fused in Sarcoma (FUS) proteinopathy is a feature of frontotemporal lobar dementia (FTLD),
and mutation of the fus gene segregates with FTLD and amyotrophic lateral sclerosis (ALS) …

Although a great knowledge about the patho‐physiological roles of cholesterol metabolism
perturbation in several organs has been reached, scarce information is available on the …

The cognitive function impairment may be related to the inflammation of the hippocampus in
Parkinson's disease. Simvastatin can play a positive role in Parkinson's disease. The …

Statins are some of the most commonly prescribed drugs and are used to reduce blood
cholesterol. Recent evidence suggests that, in some patients, they may adversely influence …

The aim of the present work was to shed light on the role played by the
isoprenoid/cholesterol biosynthetic pathway in the modulation of emotional reactivity and …

The precise subsynaptic organization of proteins at the postsynaptic membrane controls
synaptic transmission. In particular, postsynaptic receptor complexes are concentrated in …

During differentiation, neurons acquire their typical shape and functional properties. At
present, it is unclear, whether this important developmental step involves metabolic …