[HTML][HTML] Adaptive immune receptor germline gene variation
MM Corcoran, GBK Hedestam - Current Opinion in Immunology, 2024 - Elsevier
Recognition of antigens by T cell receptors (TCRs) and B cell receptors (BCRs) is a key step
in lymphocyte activation. T and B cells mediate adaptive immune responses, which protect …
in lymphocyte activation. T and B cells mediate adaptive immune responses, which protect …
Targeted long-read sequencing facilitates phased diploid assembly and genotyping of the human T cell receptor alpha, delta, and beta loci
OL Rodriguez, CA Silver, K Shields, ML Smith… - Cell Genomics, 2022 - cell.com
T cell receptors (TCRs) recognize peptide fragments presented by the major
histocompatibility complex (MHC) and are critical to T cell-mediated immunity. Recent data …
histocompatibility complex (MHC) and are critical to T cell-mediated immunity. Recent data …
Digger: directed annotation of immunoglobulin and T cell receptor V, D, and J gene sequences and assemblies
Knowledge of immunoglobulin and T cell receptor encoding genes is derived from high-
quality genomic sequencing. High-throughput sequencing is delivering large volumes of …
quality genomic sequencing. High-throughput sequencing is delivering large volumes of …
[HTML][HTML] A novel framework for human leukocyte antigen (HLA) genotyping using probe capture-based targeted next-generation sequencing and computational …
SK Lai, AC Luo, IH Chiu, HW Chuang, TH Chou… - Computational and …, 2024 - Elsevier
Human leukocyte antigen (HLA) genes play pivotal roles in numerous immunological
applications. Given the immense number of polymorphisms, achieving accurate high …
applications. Given the immense number of polymorphisms, achieving accurate high …
IGLoo: Profiling the Immunoglobulin Heavy chain locus in Lymphoblastoid Cell Lines with PacBio High-Fidelity Sequencing reads
New high-quality human genome assemblies derived from lymphoblastoid cell lines (LCLs)
provide reference genomes and pangenomes for genomics studies. However, the …
provide reference genomes and pangenomes for genomics studies. However, the …
[HTML][HTML] AIRR community curation and standardised representation for immunoglobulin and T cell receptor germline sets
Abstract Analysis of an individual's immunoglobulin or T cell receptor gene repertoire can
provide important insights into immune function. High-quality analysis of adaptive immune …
provide important insights into immune function. High-quality analysis of adaptive immune …
Airr Community Curation and Standardised Representation for Immunoglobulin and T Cell Receptor Germline Sets
Abstract Analysis of an individual's immunoglobulin or T cell receptor gene repertoire can
provide important insights into immune function. High-quality analysis of adaptive immune …
provide important insights into immune function. High-quality analysis of adaptive immune …