Overcoming trastuzumab resistance in HER2‐positive breast cancer using combination therapy

A Derakhshani, Z Rezaei, H Safarpour… - Journal of cellular …, 2020 - Wiley Online Library
Human epidermal growth factor receptor 2 (HER2)‐positive breast cancer (BC) comprises
around 20–30% of all BC subtypes and is correlated with poor prognosis. For many years …

[HTML][HTML] Roles and mechanisms of miR-195–5p in human solid cancers

Q Xu, JL Xu, WQ Chen, WX Xu, YX Song… - Biomedicine & …, 2022 - Elsevier
Cancer persists as a worldwide disease that contributes to high morbidity and mortality
rates. As a class of non-coding RNA, microRNAs (miRNAs) are one kind of important …

MiR-132 inhibits migration and invasion and increases chemosensitivity of cisplatin-resistant oral squamous cell carcinoma cells via targeting TGF-β1

L Chen, Q Zhu, L Lu, Y Liu - Bioengineered, 2020 - Taylor & Francis
Numerous findings have demonstrated that MicroRNAs dysregulation plays a key role in
many neoplasms, including oral squamous cell carcinoma (OSCC), yet the potential …

Gene expression and miRNAs profiling: function and regulation in human epidermal growth factor receptor 2 (HER2)-positive breast cancer

RM Sareyeldin, I Gupta, I Al-Hashimi, HA Al-Thawadi… - Cancers, 2019 - mdpi.com
Breast cancer is the second most common cause of cancer-related deaths among women
worldwide. It is a heterogeneous disease with four major molecular subtypes. One of the …

[HTML][HTML] miR-340: A multifunctional role in human malignant diseases

Z Huang, Y Xu, M Wan, X Zeng, J Wu - International Journal of …, 2021 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are a class of short non-coding RNAs of approximately 22 nucleotides
in length, which function by binding to the 3'UTR sequences of their target mRNAs. It has …

The role of MicroRNAs in HER2-Positive breast Cancer: where we are and future prospective

V Fogazzi, M Kapahnke, A Cataldo, I Plantamura… - Cancers, 2022 - mdpi.com
Simple Summary Breast cancer is the most diagnosed malignancy in woman worldwide
and, despite the availability of new innovative therapies, it remains the first cause of death …

Development of a microRNA panel for classification of abnormal mammograms for breast cancer

R Zou, SY Loke, VKM Tan, ST Quek, P Jagmohan… - Cancers, 2021 - mdpi.com
Simple Summary Breast cancer screening by mammography suffers from high rates of false
positivity, resulting in unnecessary investigative imaging and biopsies. There is an unmet …

Effect of polyphenols on HER2-positive breast cancer and related miRNAs: Epigenomic regulation

ME Zabaleta, TY Forbes-Hernández… - Food Research …, 2020 - Elsevier
HER2-positive breast cancer is one of the most aggressive subtypes accounting for nearly
30% of diagnosed cases. It is associated with reduced disease-free survival, tumor …

[HTML][HTML] Propofol reduces epithelial to mesenchymal transition, invasion and migration of gastric cancer cells through the microRNA-195-5p/snail axis

F Liu, F Qiu, M Fu, H Chen, H Wang - Medical Science Monitor …, 2020 - ncbi.nlm.nih.gov
Propofol Reduces Epithelial to Mesenchymal Transition, Invasion and Migration of Gastric
Cancer Cells through the MicroRNA-195-5p/Snail Axis - PMC Back to Top Skip to main content …

Targeted therapy modulates the secretome of cancer-associated fibroblasts to induce resistance in HER2-positive breast cancer

M Luque, M Sanz-Álvarez, A Santamaría… - International Journal of …, 2021 - mdpi.com
The combination of trastuzumab plus pertuzumab plus docetaxel as a first-line therapy in
patients with HER2-positive metastatic breast cancer has provided significant clinical …