[HTML][HTML] Clinical diagnostic biomarker “circulating tumor cells” in breast cancer-a meta-analysis

S Bai, S Lin, T Lin, Q Wang, C Cheng, J Lin… - Frontiers in …, 2023 - frontiersin.org
Objective Using meta-analysis, we evaluate circulating tumor cells (CTCs) as a potential
diagnostic tool for breast cancer. Methods A document search was conducted using publicly …

[HTML][HTML] Affinity probes based on small-molecule inhibitors for tumor imaging

X Yi, Z Wang, X Hu, A Yu - Frontiers in Oncology, 2022 - frontiersin.org
Methods for molecular imaging of target areas, including optical imaging, radionuclide
imaging, magnetic resonance imaging and other imaging technologies, are helpful for the …

Development of rofecoxib-based fluorescent probes and investigations on their solvatochromism, AIE activity, mechanochromism, and COX-2-targeted bioimaging

L Xie, R Li, B Zheng, Z Xie, X Fang, Y Wang… - Analytical …, 2021 - ACS Publications
Cyclooxygenase-2 (COX-2) fluorescent probes are promising tools for early diagnosis of
cancer. Traditionally, COX-2 probes were designed by connecting two parts, a fluorophore …

One-step transformation from rofecoxib to a COX-2 NIR probe for human cancer tissue/organoid targeted bioimaging

L Xie, R Li, B Zheng, Z Xie, X Fang, T Dai… - ACS Applied Bio …, 2021 - ACS Publications
COX-2 fluorescent probes are promising tools for cancer diagnosis. Such probes have been
conventionally designed by conjugating a fluorophore to COX-2 inhibitors through lengthy …

Development of Rofecoxib‐Based Fluorophores from ACQ to AIE by Positional Regioisomerization

X Wang, L Chen, R Li, Z Xie, M Hu, S Sun, Z Li… - …, 2022 - Wiley Online Library
The development of aggregation‐induced emission luminogens (AIEgens) has attracted
increasing attention due to their potential applications in various areas in recent years. In …

Comparison of absolute expression and turnover number of COX-1 and COX-2 in human and rodent cells and tissues

L Li, R Sun, J Zenga, H Himburg, L Wang… - Journal of …, 2022 - Taylor & Francis
Objective We aim to quantify the absolute protein expression of cyclooxygenase-1 (COX-1)
and cyclooxygenase-2 (COX-2) in various cells and tissues to determine the relative …

Triple-responsive targeted hybrid liposomes with high MRI performance for tumor diagnosis and therapy

W Yao, C Liu, N Wang, H Zhou, H Chen… - Materials Chemistry …, 2021 - pubs.rsc.org
Targeted multi-responsive drug delivery systems with magnetic resonance imaging (MRI)
capacity were anticipated as a promising tool for tumor therapy and diagnosis. Herein, we …

Development of Rofecoxib-Based Fluorescent Probes and Investigations on Their AIE Activity, Solvatochromism, Mechanochromism and COX-2 Targeted Bioimaging

L Xie, R Li, B Zheng, Z Xie, X Fang, Y Wang, G Cuny… - 2021 - chemrxiv.org
Cyclooxygenase-2 (COX-2) fluorescent probes are promising tools for early cancer
diagnosis. Traditionally, COX-2 probes were designed by connecting two parts, a …

Selective Cyclooxygenase-2 Inhibitors and Familial Adenomatous Polyposis (FAP): Investigation of Colonic COX-2 as a Target for Chemoprevention in Pirc Rats

L Li - 2021 - uh-ir.tdl.org
Objective: The objective of this project is to evaluate the chemoprevention efficacy of locally
bioavailable and selective COX-2 inhibitor 6a1 by using Pirc rat model with DSS …