[HTML][HTML] Forkhead Box O signaling pathway in skeletal muscle atrophy

K Chen, P Gao, Z Li, A Dai, M Yang, S Chen… - The American Journal of …, 2022 - Elsevier
Skeletal muscle atrophy is the consequence of protein degradation exceeding protein
synthesis because of disease, aging, and physical inactivity. Patients with skeletal muscle …

Good or not good: Role of miR-18a in cancer biology

T Kolenda, K Guglas, M Kopczyńska… - Reports of Practical …, 2020 - journals.viamedica.pl
Abstract miR-18a is a member of primary transcript called miR-17-92a (C13orf25 or
MIR17HG) which also contains five other miRNAs: miR-17, miR-19a, miR-20a, miR-19b and …

The role of IGF-1 signaling in skeletal muscle atrophy

LT Timmer, WMH Hoogaars, RT Jaspers - Muscle Atrophy, 2018 - Springer
Insulin-like growth factor 1 (IGF-1) is a key anabolic growth factor stimulating
phosphatidylinositol 3-kinase (PI3K)/Akt signaling which is well known for regulating muscle …

[HTML][HTML] CircCCDC91 regulates chicken skeletal muscle development by sponging miR-15 family via activating IGF1-PI3K/AKT signaling pathway

J Zhao, X Zhao, X Shen, Y Zhang, Y Zhang, L Ye, D Li… - Poultry science, 2022 - Elsevier
Circular RNAs (circRNAs) has been reported in various tissues of animals and associated
with multiple biological processes. From our previous sequencing data, we found a novel …

Identification of microRNAs in skeletal muscle associated with lung cancer cachexia

WRPH van De Worp, AMWJ Schols… - Journal of cachexia …, 2020 - Wiley Online Library
Background Cachexia, highly prevalent in patients with non‐small cell lung cancer
(NSCLC), impairs quality of life and is associated with reduced tolerance and …

LncRNA CASC2 is involved in the development of chronic obstructive pulmonary disease via targeting miR-18a-5p/IGF1 axis

P Liu, H Zhang, H Zeng, Y Meng… - Therapeutic …, 2021 - journals.sagepub.com
Aims: Chronic obstructive pulmonary disease (COPD) is a systemic disease. Several long
non-coding RNAs (lncRNAs) have been identified to be aberrantly expressed in COPD …

Skeletal muscle wasting in chronic kidney disease: the emerging role of microRNAs

KA Robinson, LA Baker… - Nephrology Dialysis …, 2020 - academic.oup.com
Skeletal muscle wasting is a common complication of chronic kidney disease (CKD),
characterized by the loss of muscle mass, strength and function, which significantly …

Effects of plantar mechanical stimulation on anabolic and catabolic signaling in rat postural muscle under short-term simulated gravitational unloading

SA Tyganov, EP Mochalova, SP Belova… - Frontiers in …, 2019 - frontiersin.org
It is known that plantar mechanical stimulation (PMS) is able to attenuate unloading-induced
skeletal muscle atrophy and impaired muscle function. However, molecular mechanisms …

Regulation of skeletal muscle atrophy in cachexia by microRNAs and long non-coding RNAs

R Chen, S Lei, T Jiang, Y She, H Shi - Frontiers in cell and …, 2020 - frontiersin.org
Skeletal muscle atrophy is a common complication of cachexia, characterized by
progressive bodyweight loss and decreased muscle strength, and it significantly increases …

Emerging role of MyomiRs as biomarkers and therapeutic targets in skeletal muscle diseases

S Srivastava, R Rathor, SN Singh… - American Journal of …, 2021 - journals.physiology.org
Several chronic diseases lead to skeletal muscle loss and a decline in physical
performance. MicroRNAs (miRNAs) are small, noncoding RNAs, which have exhibited their …