Thyroid cancer (TC) is the eighth most frequently diagnosed cancer worldwide with a rising
incidence in the past 20 years. Surgery is the primary strategy of therapy for patients with …

Chromatin-based DNA damage response (DDR) pathways are fundamental for preventing
genome and epigenome instability, which are prevalent in cancer. Histone …

Abstract Belinostat [Beleodaq®(US)], a small-molecule hydroxamate-type inhibitor of class I,
II and IV histone deacetylase (HDAC) enzymes, has been developed by TopoTarget and …

Neutrophils undergo a unique form of cell death that generates neutrophil extracellular traps
(NETs) that may help to neutralize invading pathogens and restore homeostasis. However …

Context: Anaplastic thyroid cancer (ATC) is the most lethal of all thyroid cancers and one of
the most aggressive human carcinomas. In the search for effective treatment options …

Peripheral T-cell lymphoma is a heterogenous non-Hodgkin Lymphoma with historically
poor outcomes. Currently, response rates remain poor with traditional chemotherapy and …

Anaplastic thyroid cancer (ATC) represents one of the most lethal human cancers and
although this tumor type is rare, ATC accounts for the majority of deaths from thyroid cancer …

Well-differentiated thyroid cancer accounts for the majority of endocrine malignancies and,
in general, has an excellent prognosis. In contrast, the less common poorly differentiated …

Background: Anaplastic thyroid carcinoma (ATC) is one of the most aggressive
malignancies, with no effective treatment currently available. The molecular mechanisms of …

Background: No standard chemotherapy is available for anaplastic thyroid cancer (ATC).
Drug-loaded nanobubbles (NBs) are a promising innovative anticancer drug formulation …