The multiplex model of the genetics of Alzheimer's disease
Genes play a strong role in Alzheimer's disease (AD), with late-onset AD showing heritability
of 58–79% and early-onset AD showing over 90%. Genetic association provides a robust …
of 58–79% and early-onset AD showing over 90%. Genetic association provides a robust …
[HTML][HTML] Quantitative mapping of the brain's structural connectivity using diffusion MRI tractography: A review
Diffusion magnetic resonance imaging (dMRI) tractography is an advanced imaging
technique that enables in vivo reconstruction of the brain's white matter connections at …
technique that enables in vivo reconstruction of the brain's white matter connections at …
A cross-disorder connectome landscape of brain dysconnectivity
MP van den Heuvel, O Sporns - Nature reviews neuroscience, 2019 - nature.com
Many human brain disorders are associated with characteristic alterations in the structural
and functional connectivity of the brain. In this article, we explore how commonalities and …
and functional connectivity of the brain. In this article, we explore how commonalities and …
Understanding disease progression and improving Alzheimer's disease clinical trials: Recent highlights from the Alzheimer's Disease Neuroimaging Initiative
DP Veitch, MW Weiner, PS Aisen, LA Beckett… - Alzheimer's & …, 2019 - Elsevier
Introduction The overall goal of the Alzheimer's Disease Neuroimaging Initiative (ADNI) is to
validate biomarkers for Alzheimer's disease (AD) clinical trials. ADNI is a multisite …
validate biomarkers for Alzheimer's disease (AD) clinical trials. ADNI is a multisite …
Structural brain abnormalities in the common epilepsies assessed in a worldwide ENIGMA study
Progressive functional decline in the epilepsies is largely unexplained. We formed the
ENIGMA-Epilepsy consortium to understand factors that influence brain measures in …
ENIGMA-Epilepsy consortium to understand factors that influence brain measures in …
Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder working group
The pattern of structural brain alterations associated with major depressive disorder (MDD)
remains unresolved. This is in part due to small sample sizes of neuroimaging studies …
remains unresolved. This is in part due to small sample sizes of neuroimaging studies …
Cortical thickness across the lifespan: Data from 17,075 healthy individuals aged 3–90 years
Delineating the association of age and cortical thickness in healthy individuals is critical
given the association of cortical thickness with cognition and behavior. Previous research …
given the association of cortical thickness with cognition and behavior. Previous research …
Interpreting and utilising intersubject variability in brain function
ML Seghier, CJ Price - Trends in cognitive sciences, 2018 - cell.com
We consider between-subject variance in brain function as data rather than noise. We
describe variability as a natural output of a noisy plastic system (the brain) where each …
describe variability as a natural output of a noisy plastic system (the brain) where each …
Distinct subcortical volume alterations in pediatric and adult OCD: a worldwide meta-and mega-analysis
PSW Boedhoe, L Schmaal, Y Abe… - American Journal of …, 2017 - Am Psychiatric Assoc
Objective: Structural brain imaging studies in obsessive-compulsive disorder (OCD) have
produced inconsistent findings. This may be partially due to limited statistical power from …
produced inconsistent findings. This may be partially due to limited statistical power from …
Recent publications from the Alzheimer's Disease Neuroimaging Initiative: Reviewing progress toward improved AD clinical trials
MW Weiner, DP Veitch, PS Aisen, LA Beckett… - Alzheimer's & …, 2017 - Elsevier
Abstract Introduction The Alzheimer's Disease Neuroimaging Initiative (ADNI) has continued
development and standardization of methodologies for biomarkers and has provided an …
development and standardization of methodologies for biomarkers and has provided an …