The role of miRNAs in liver diseases: Potential therapeutic and clinical applications
MicroRNAs (miRNAs) are a class of short, non-coding RNAs that function post-
transcriptionally to regulate gene expression by binding to particular mRNA targets and …
transcriptionally to regulate gene expression by binding to particular mRNA targets and …
MicroRNAs as regulators, biomarkers and therapeutic targets in liver diseases
MicroRNAs (miRNAs) are small, non-coding RNAs that post-transcriptionally regulate gene
expression by binding to specific mRNA targets and promoting their degradation and/or …
expression by binding to specific mRNA targets and promoting their degradation and/or …
Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression
M Qi, Y Xia, Y Wu, Z Zhang, X Wang, L Lu, C Dai… - Nature …, 2022 - nature.com
The formation of pre-metastatic niche is a key step in the metastatic burden. The pluripotent
factor Lin28B is frequently expressed in breast tumors and is particularly upregulated in the …
factor Lin28B is frequently expressed in breast tumors and is particularly upregulated in the …
MicroRNA let-7 and viral infections: focus on mechanisms of action
A Letafati, S Najafi, M Mottahedi, M Karimzadeh… - Cellular & molecular …, 2022 - Springer
MicroRNAs (miRNAs) are fundamental post-transcriptional modulators of several critical
cellular processes, a number of which are involved in host defense mechanisms. In …
cellular processes, a number of which are involved in host defense mechanisms. In …
Extracellular vesicles as biomarkers in liver diseases: A clinician's point of view
S Thietart, PE Rautou - Journal of hepatology, 2020 - Elsevier
Extracellular vesicles are membrane-bound vesicles containing proteins, lipids, RNAs and
microRNAs. They can originate from both healthy and stressed cells, and provide a …
microRNAs. They can originate from both healthy and stressed cells, and provide a …
Molecular and functional roles of microRNAs in the progression of hepatocellular carcinoma—a review
K Oura, A Morishita, T Masaki - International journal of molecular sciences, 2020 - mdpi.com
Liver cancer is the fourth leading cause of cancer deaths globally, of which hepatocellular
carcinoma (HCC) is the major subtype. Viral hepatitis B and C infections, alcohol abuse, and …
carcinoma (HCC) is the major subtype. Viral hepatitis B and C infections, alcohol abuse, and …
Mechanisms underlying hepatitis C virus-associated hepatic fibrosis
Hepatitis C virus (HCV) infection often causes liver diseases, including fibrosis, cirrhosis and
hepatocellular carcinoma (HCC). Liver fibrosis is the outcome of the wound healing …
hepatocellular carcinoma (HCC). Liver fibrosis is the outcome of the wound healing …
MicroRNAs in the pathogenesis of hepatocellular carcinoma: a review
A Morishita, K Oura, T Tadokoro, K Fujita, J Tani… - Cancers, 2021 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is one of the most frequently occurring
cancers, and the prognosis for late-stage HCC remains poor. A better understanding of the …
cancers, and the prognosis for late-stage HCC remains poor. A better understanding of the …
MicroRNA-223 ameliorates alcoholic liver injury by inhibiting the IL-6–p47phox–oxidative stress pathway in neutrophils
Objectives Chronic-plus-binge ethanol feeding activates neutrophils and exacerbates liver
injury in mice. This study investigates how recent excessive drinking affects peripheral …
injury in mice. This study investigates how recent excessive drinking affects peripheral …
miRNAs as potential biomarkers for viral hepatitis B and C
D Loureiro, I Tout, S Narguet, SM Benazzouz… - Viruses, 2020 - mdpi.com
Around 257 million people are living with hepatitis B virus (HBV) chronic infection and 71
million with hepatitis C virus (HCV) chronic infection. Both HBV and HCV infections can lead …
million with hepatitis C virus (HCV) chronic infection. Both HBV and HCV infections can lead …